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EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF, Milner J, Brown LA, Hsu F, Gilks B, Nielsen T, Schulzer M, Chia S, Ragaz J, Cahn A, Linger L, Ozdag H, Cattaneo E, Jordanova ES, Schuuring E, Yu DS, Venkitaraman A, Ponder B, Doherty A, Aparicio S, Bentley D, Theillet C, Ponting CP, Caldas C, Kouzarides T. Hughes-Davies L, et al. Cell. 2003 Nov 26;115(5):523-35. doi: 10.1016/s0092-8674(03)00930-9. Cell. 2003. PMID: 14651845 Free article.
Crystal structure of the ENT domain of human EMSY.
Chavali GB, Ekblad CM, Basu BP, Brissett NC, Veprintsev D, Hughes-Davies L, Kouzarides T, Itzhaki LS, Doherty AJ. Chavali GB, et al. J Mol Biol. 2005 Jul 29;350(5):964-73. doi: 10.1016/j.jmb.2005.05.047. J Mol Biol. 2005. PMID: 15978617
Transcriptional activation functions in BRCA2.
Milner J, Ponder B, Hughes-Davies L, Seltmann M, Kouzarides T. Milner J, et al. Nature. 1997 Apr 24;386(6627):772-3. doi: 10.1038/386772a0. Nature. 1997. PMID: 9126734 No abstract available.
Tamoxifen: the drug that came in from the cold.
Hughes-Davies L, Caldas C, Wishart GC. Hughes-Davies L, et al. Br J Cancer. 2009 Sep 15;101(6):875-8. doi: 10.1038/sj.bjc.6605231. Epub 2009 Aug 11. Br J Cancer. 2009. PMID: 19672259 Free PMC article. Review.
Disease-free and overall survival at 3.5 years for neoadjuvant bevacizumab added to docetaxel followed by fluorouracil, epirubicin and cyclophosphamide, for women with HER2 negative early breast cancer: ARTemis Trial.
Earl HM, Hiller L, Dunn JA, Blenkinsop C, Grybowicz L, Vallier AL, Gounaris I, Abraham JE, Hughes-Davies L, McAdam K, Chan S, Ahmad R, Hickish T, Rea D, Caldas C, Bartlett JMS, Cameron DA, Provenzano E, Thomas J, Hayward RL; ARTemis Investigators Group. Earl HM, et al. Ann Oncol. 2017 Aug 1;28(8):1817-1824. doi: 10.1093/annonc/mdx173. Ann Oncol. 2017. PMID: 28459938 Free PMC article. Clinical Trial.
55 results