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Tissue production of pro-inflammatory cytokines (IL-1beta, TNFalpha and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis.
Hernández-Rodríguez J, Segarra M, Vilardell C, Sánchez M, García-Martínez A, Esteban MJ, Queralt C, Grau JM, Urbano-Márquez A, Palacín A, Colomer D, Cid MC. Hernández-Rodríguez J, et al. Among authors: segarra m. Rheumatology (Oxford). 2004 Mar;43(3):294-301. doi: 10.1093/rheumatology/keh058. Epub 2003 Dec 16. Rheumatology (Oxford). 2004. PMID: 14679293
Increased expression of the endothelin system in arterial lesions from patients with giant-cell arteritis: association between elevated plasma endothelin levels and the development of ischaemic events.
Lozano E, Segarra M, Corbera-Bellalta M, García-Martínez A, Espígol-Frigolé G, Plà-Campo A, Hernández-Rodríguez J, Cid MC. Lozano E, et al. Among authors: segarra m. Ann Rheum Dis. 2010 Feb;69(2):434-42. doi: 10.1136/ard.2008.105692. Epub 2009 Mar 15. Ann Rheum Dis. 2010. PMID: 19289383
Elevated production of interleukin-6 is associated with a lower incidence of disease-related ischemic events in patients with giant-cell arteritis: angiogenic activity of interleukin-6 as a potential protective mechanism.
Hernández-Rodríguez J, Segarra M, Vilardell C, Sánchez M, García-Martínez A, Esteban MJ, Grau JM, Urbano-Márquez A, Colomer D, Kleinman HK, Cid MC. Hernández-Rodríguez J, et al. Among authors: segarra m. Circulation. 2003 May 20;107(19):2428-34. doi: 10.1161/01.CIR.0000066907.83923.32. Epub 2003 May 12. Circulation. 2003. PMID: 12742994 Clinical Trial.
Gelatinase expression and proteolytic activity in giant-cell arteritis.
Segarra M, García-Martínez A, Sánchez M, Hernández-Rodríguez J, Lozano E, Grau JM, Cid MC. Segarra M, et al. Ann Rheum Dis. 2007 Nov;66(11):1429-35. doi: 10.1136/ard.2006.068148. Epub 2007 May 14. Ann Rheum Dis. 2007. PMID: 17502363 Free PMC article.
Clinical relevance of persistently elevated circulating cytokines (tumor necrosis factor alpha and interleukin-6) in the long-term followup of patients with giant cell arteritis.
García-Martínez A, Hernández-Rodríguez J, Espígol-Frigolé G, Prieto-González S, Butjosa M, Segarra M, Lozano E, Cid MC. García-Martínez A, et al. Among authors: segarra m. Arthritis Care Res (Hoboken). 2010 Jun;62(6):835-41. doi: 10.1002/acr.20043. Arthritis Care Res (Hoboken). 2010. PMID: 20535794 Free article.
Increased IL-17A expression in temporal artery lesions is a predictor of sustained response to glucocorticoid treatment in patients with giant-cell arteritis.
Espígol-Frigolé G, Corbera-Bellalta M, Planas-Rigol E, Lozano E, Segarra M, García-Martínez A, Prieto-González S, Hernández-Rodríguez J, Grau JM, Rahman MU, Cid MC. Espígol-Frigolé G, et al. Among authors: segarra m. Ann Rheum Dis. 2013 Sep 1;72(9):1481-7. doi: 10.1136/annrheumdis-2012-201836. Epub 2012 Sep 19. Ann Rheum Dis. 2013. PMID: 22993227 Clinical Trial.
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