Kirsch GE - Search Results

1

Mechanisms by which SCN5A mutation N1325S causes cardiac arrhythmias and sudden death in vivo.

Tian XL, Yong SL, Wan X, Wu L, Chung MK, Tchou PJ, Rosenbaum DS, Van Wagoner DR, Kirsch GE, Wang Q. Tian XL, et al. Among authors: kirsch ge. Cardiovasc Res. 2004 Feb 1;61(2):256-67. doi: 10.1016/j.cardiores.2003.11.007. Cardiovasc Res. 2004. PMID: 14736542 Free PMC article.

2

Hysteresis effect implicates calcium cycling as a mechanism of repolarization alternans.

Walker ML, Wan X, Kirsch GE, Rosenbaum DS. Walker ML, et al. Among authors: kirsch ge. Circulation. 2003 Nov 25;108(21):2704-9. doi: 10.1161/01.CIR.0000093276.10885.5B. Epub 2003 Oct 27. Circulation. 2003. PMID: 14581412

3

Functional suppression of sodium channels by beta(1)-subunits as a molecular mechanism of idiopathic ventricular fibrillation.

Wan X, Wang Q, Kirsch GE. Wan X, et al. Among authors: kirsch ge. J Mol Cell Cardiol. 2000 Oct;32(10):1873-84. doi: 10.1006/jmcc.2000.1223. J Mol Cell Cardiol. 2000. PMID: 11013131

4

Accelerated inactivation in a mutant Na(+) channel associated with idiopathic ventricular fibrillation.

Wan X, Chen S, Sadeghpour A, Wang Q, Kirsch GE. Wan X, et al. Among authors: kirsch ge. Am J Physiol Heart Circ Physiol. 2001 Jan;280(1):H354-60. doi: 10.1152/ajpheart.2001.280.1.H354. Am J Physiol Heart Circ Physiol. 2001. PMID: 11123251 Free article.

5

The common SCN5A mutation R1193Q causes LQTS-type electrophysiological alterations of the cardiac sodium channel.

Wang Q, Chen S, Chen Q, Wan X, Shen J, Hoeltge GA, Timur AA, Keating MT, Kirsch GE. Wang Q, et al. Among authors: kirsch ge. J Med Genet. 2004 May;41(5):e66. doi: 10.1136/jmg.2003.013300. J Med Genet. 2004. PMID: 15121794 Free PMC article. No abstract available.

6

Multiple mechanisms of Na+ channel--linked long-QT syndrome.

Dumaine R, Wang Q, Keating MT, Hartmann HA, Schwartz PJ, Brown AM, Kirsch GE. Dumaine R, et al. Among authors: kirsch ge. Circ Res. 1996 May;78(5):916-24. doi: 10.1161/01.res.78.5.916. Circ Res. 1996. PMID: 8620612

7

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation.

Chen Q, Kirsch GE, Zhang D, Brugada R, Brugada J, Brugada P, Potenza D, Moya A, Borggrefe M, Breithardt G, Ortiz-Lopez R, Wang Z, Antzelevitch C, O'Brien RE, Schulze-Bahr E, Keating MT, Towbin JA, Wang Q. Chen Q, et al. Among authors: kirsch ge. Nature. 1998 Mar 19;392(6673):293-6. doi: 10.1038/32675. Nature. 1998. PMID: 9521325

8

Increased cardiac risk in concomitant methadone and diazepam treatment: pharmacodynamic interactions in cardiac ion channels.

Kuryshev YA, Bruening-Wright A, Brown AM, Kirsch GE. Kuryshev YA, et al. Among authors: kirsch ge. J Cardiovasc Pharmacol. 2010 Oct;56(4):420-30. doi: 10.1097/FJC.0b013e3181f1d21b. J Cardiovasc Pharmacol. 2010. PMID: 20930594

9

Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts.

Brugada R, Brugada J, Antzelevitch C, Kirsch GE, Potenza D, Towbin JA, Brugada P. Brugada R, et al. Among authors: kirsch ge. Circulation. 2000 Feb 8;101(5):510-5. doi: 10.1161/01.cir.101.5.510. Circulation. 2000. PMID: 10662748

10

Mechanism of lidocaine block of late current in long Q-T mutant Na+ channels.

Dumaine R, Kirsch GE. Dumaine R, et al. Among authors: kirsch ge. Am J Physiol. 1998 Feb;274(2):H477-87. doi: 10.1152/ajpheart.1998.274.2.H477. Am J Physiol. 1998. PMID: 9486250

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