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Genetic factors and insulin secretion: gene variants in the IGF genes.
't Hart LM, Fritsche A, Rietveld I, Dekker JM, Nijpels G, Machicao F, Stumvoll M, van Duijn CM, Häring HU, Heine RJ, Maassen JA, van Haeften TW. 't Hart LM, et al. Among authors: nijpels g. Diabetes. 2004 Feb;53 Suppl 1:S26-30. doi: 10.2337/diabetes.53.2007.s26. Diabetes. 2004. PMID: 14749262 Free article.
Mitochondrial diabetes: molecular mechanisms and clinical presentation.
Maassen JA, 'T Hart LM, Van Essen E, Heine RJ, Nijpels G, Jahangir Tafrechi RS, Raap AK, Janssen GM, Lemkes HH. Maassen JA, et al. Among authors: nijpels g. Diabetes. 2004 Feb;53 Suppl 1:S103-9. doi: 10.2337/diabetes.53.2007.s103. Diabetes. 2004. PMID: 14749274 Review.
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.
't Hart LM, Hansen T, Rietveld I, Dekker JM, Nijpels G, Janssen GM, Arp PA, Uitterlinden AG, Jørgensen T, Borch-Johnsen K, Pols HA, Pedersen O, van Duijn CM, Heine RJ, Maassen JA. 't Hart LM, et al. Among authors: nijpels g. Diabetes. 2005 Jun;54(6):1892-5. doi: 10.2337/diabetes.54.6.1892. Diabetes. 2005. PMID: 15919814 Free article.
Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps.
't Hart LM, Simonis-Bik AM, Nijpels G, van Haeften TW, Schäfer SA, Houwing-Duistermaat JJ, Boomsma DI, Groenewoud MJ, Reiling E, van Hove EC, Diamant M, Kramer MH, Heine RJ, Maassen JA, Kirchhoff K, Machicao F, Häring HU, Slagboom PE, Willemsen G, Eekhoff EM, de Geus EJ, Dekker JM, Fritsche A. 't Hart LM, et al. Among authors: nijpels g. Diabetes. 2010 Jan;59(1):287-92. doi: 10.2337/db09-0736. Epub 2009 Oct 6. Diabetes. 2010. PMID: 19808892 Free PMC article.
Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function.
Simonis-Bik AM, Nijpels G, van Haeften TW, Houwing-Duistermaat JJ, Boomsma DI, Reiling E, van Hove EC, Diamant M, Kramer MH, Heine RJ, Maassen JA, Slagboom PE, Willemsen G, Dekker JM, Eekhoff EM, de Geus EJ, 't Hart LM. Simonis-Bik AM, et al. Among authors: nijpels g. Diabetes. 2010 Jan;59(1):293-301. doi: 10.2337/db09-1048. Epub 2009 Oct 15. Diabetes. 2010. PMID: 19833888 Free PMC article.
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.
Wood AR, Jonsson A, Jackson AU, Wang N, van Leewen N, Palmer ND, Kobes S, Deelen J, Boquete-Vilarino L, Paananen J, Stančáková A, Boomsma DI, de Geus EJC, Eekhoff EMW, Fritsche A, Kramer M, Nijpels G, Simonis-Bik A, van Haeften TW, Mahajan A, Boehnke M, Bergman RN, Tuomilehto J, Collins FS, Mohlke KL, Banasik K, Groves CJ, McCarthy MI; Diabetes Research on Patient Stratification (DIRECT); Pearson ER, Natali A, Mari A, Buchanan TA, Taylor KD, Xiang AH, Gjesing AP, Grarup N, Eiberg H, Pedersen O, Chen YD, Laakso M, Norris JM, Smith U, Wagenknecht LE, Baier L, Bowden DW, Hansen T, Walker M, Watanabe RM, 't Hart LM, Hanson RL, Frayling TM. Wood AR, et al. Among authors: nijpels g. Diabetes. 2017 Aug;66(8):2296-2309. doi: 10.2337/db16-1452. Epub 2017 May 10. Diabetes. 2017. PMID: 28490609 Free PMC article.
473 results