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Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation.
Yasuda N, Miura S, Akazawa H, Tanaka T, Qin Y, Kiya Y, Imaizumi S, Fujino M, Ito K, Zou Y, Fukuhara S, Kunimoto S, Fukuzaki K, Sato T, Ge J, Mochizuki N, Nakaya H, Saku K, Komuro I. Yasuda N, et al. Among authors: mochizuki n. EMBO Rep. 2008 Feb;9(2):179-86. doi: 10.1038/sj.embor.7401157. Epub 2008 Jan 18. EMBO Rep. 2008. PMID: 18202720 Free PMC article.
Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling.
Shioyama W, Nakaoka Y, Higuchi K, Minami T, Taniyama Y, Nishida K, Kidoya H, Sonobe T, Naito H, Arita Y, Hashimoto T, Kuroda T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I. Shioyama W, et al. Among authors: mochizuki n. Circ Res. 2011 Mar 18;108(6):664-75. doi: 10.1161/CIRCRESAHA.110.232223. Epub 2011 Feb 3. Circ Res. 2011. PMID: 21293003
Calpain protects the heart from hemodynamic stress.
Taneike M, Mizote I, Morita T, Watanabe T, Hikoso S, Yamaguchi O, Takeda T, Oka T, Tamai T, Oyabu J, Murakawa T, Nakayama H, Nishida K, Takeda J, Mochizuki N, Komuro I, Otsu K. Taneike M, et al. Among authors: mochizuki n. J Biol Chem. 2011 Sep 16;286(37):32170-7. doi: 10.1074/jbc.M111.248088. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795695 Free PMC article.
Endothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and atherosclerosis in apolipoprotein E knockout mice.
Higuchi K, Nakaoka Y, Shioyama W, Arita Y, Hashimoto T, Yasui T, Ikeoka K, Kuroda T, Minami T, Nishida K, Fujio Y, Yamauchi-Takihara K, Shirai M, Mochizuki N, Komuro I. Higuchi K, et al. Among authors: mochizuki n. Circ J. 2012;76(8):2031-40. doi: 10.1253/circj.cj-11-1507. Epub 2012 May 19. Circ J. 2012. PMID: 22664868 Free article.
Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart.
Arita Y, Nakaoka Y, Matsunaga T, Kidoya H, Yamamizu K, Arima Y, Kataoka-Hashimoto T, Ikeoka K, Yasui T, Masaki T, Yamamoto K, Higuchi K, Park JS, Shirai M, Nishiyama K, Yamagishi H, Otsu K, Kurihara H, Minami T, Yamauchi-Takihara K, Koh GY, Mochizuki N, Takakura N, Sakata Y, Yamashita JK, Komuro I. Arita Y, et al. Among authors: mochizuki n. Nat Commun. 2014 Jul 29;5:4552. doi: 10.1038/ncomms5552. Nat Commun. 2014. PMID: 25072663 Free PMC article.
458 results