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Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.
Zhu K, Gerbino E, Beaupre DM, Mackley PA, Muro-Cacho C, Beam C, Hamilton AD, Lichtenheld MG, Kerr WG, Dalton W, Alsina M, Sebti SM. Zhu K, et al. Among authors: lichtenheld mg. Blood. 2005 Jun 15;105(12):4759-66. doi: 10.1182/blood-2004-11-4307. Epub 2005 Feb 22. Blood. 2005. PMID: 15728126 Free PMC article.
Potent inhibition of CTLA-4 expression by an anti-CTLA-4 ribozyme.
Cepero E, Hnatyszyn HJ, Kraus G, Lichtenheld MG. Cepero E, et al. Among authors: lichtenheld mg. Biochem Biophys Res Commun. 1998 Jun 29;247(3):838-43. doi: 10.1006/bbrc.1998.8889. Biochem Biophys Res Commun. 1998. PMID: 9647780 Free article.
41 results