Witters LA - Search Results

1

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.

Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC. Shaw RJ, et al. Among authors: witters la. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3329-35. doi: 10.1073/pnas.0308061100. Epub 2004 Feb 25. Proc Natl Acad Sci U S A. 2004. PMID: 14985505 Free PMC article.

2

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex.

Brugarolas J, Lei K, Hurley RL, Manning BD, Reiling JH, Hafen E, Witters LA, Ellisen LW, Kaelin WG Jr. Brugarolas J, et al. Among authors: witters la. Genes Dev. 2004 Dec 1;18(23):2893-904. doi: 10.1101/gad.1256804. Epub 2004 Nov 15. Genes Dev. 2004. PMID: 15545625 Free PMC article.

3

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases.

Hurley RL, Anderson KA, Franzone JM, Kemp BE, Means AR, Witters LA. Hurley RL, et al. Among authors: witters la. J Biol Chem. 2005 Aug 12;280(32):29060-6. doi: 10.1074/jbc.M503824200. Epub 2005 Jun 24. J Biol Chem. 2005. PMID: 15980064 Free article.

4

Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP.

Hurley RL, Barré LK, Wood SD, Anderson KA, Kemp BE, Means AR, Witters LA. Hurley RL, et al. Among authors: witters la. J Biol Chem. 2006 Dec 1;281(48):36662-72. doi: 10.1074/jbc.M606676200. Epub 2006 Oct 5. J Biol Chem. 2006. PMID: 17023420 Free article.

5

Dual mechanisms regulating AMPK kinase action in the ischemic heart.

Baron SJ, Li J, Russell RR 3rd, Neumann D, Miller EJ, Tuerk R, Wallimann T, Hurley RL, Witters LA, Young LH. Baron SJ, et al. Among authors: witters la. Circ Res. 2005 Feb 18;96(3):337-45. doi: 10.1161/01.RES.0000155723.53868.d2. Epub 2005 Jan 13. Circ Res. 2005. PMID: 15653571

6

Dissociation of AMP-activated protein kinase and p38 mitogen-activated protein kinase signaling in skeletal muscle.

Ho RC, Fujii N, Witters LA, Hirshman MF, Goodyear LJ. Ho RC, et al. Among authors: witters la. Biochem Biophys Res Commun. 2007 Oct 19;362(2):354-9. doi: 10.1016/j.bbrc.2007.07.154. Epub 2007 Aug 7. Biochem Biophys Res Commun. 2007. PMID: 17709097 Free PMC article.

7

Dealing with energy demand: the AMP-activated protein kinase.

Kemp BE, Mitchelhill KI, Stapleton D, Michell BJ, Chen ZP, Witters LA. Kemp BE, et al. Among authors: witters la. Trends Biochem Sci. 1999 Jan;24(1):22-5. doi: 10.1016/s0968-0004(98)01340-1. Trends Biochem Sci. 1999. PMID: 10087918 Review.

8

AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle.

Musi N, Hayashi T, Fujii N, Hirshman MF, Witters LA, Goodyear LJ. Musi N, et al. Among authors: witters la. Am J Physiol Endocrinol Metab. 2001 May;280(5):E677-84. doi: 10.1152/ajpendo.2001.280.5.E677. Am J Physiol Endocrinol Metab. 2001. PMID: 11287349 Free article.

9

PPAR alpha is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue.

Lee Y, Yu X, Gonzales F, Mangelsdorf DJ, Wang MY, Richardson C, Witters LA, Unger RH. Lee Y, et al. Among authors: witters la. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11848-53. doi: 10.1073/pnas.182420899. Epub 2002 Aug 23. Proc Natl Acad Sci U S A. 2002. PMID: 12195019 Free PMC article.

10

Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift.

Röckl KS, Hirshman MF, Brandauer J, Fujii N, Witters LA, Goodyear LJ. Röckl KS, et al. Among authors: witters la. Diabetes. 2007 Aug;56(8):2062-9. doi: 10.2337/db07-0255. Epub 2007 May 18. Diabetes. 2007. PMID: 17513699

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