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All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia.
Shen ZX, Shi ZZ, Fang J, Gu BW, Li JM, Zhu YM, Shi JY, Zheng PZ, Yan H, Liu YF, Chen Y, Shen Y, Wu W, Tang W, Waxman S, De Thé H, Wang ZY, Chen SJ, Chen Z. Shen ZX, et al. Among authors: de the h. Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5328-35. doi: 10.1073/pnas.0400053101. Epub 2004 Mar 24. Proc Natl Acad Sci U S A. 2004. PMID: 15044693 Free PMC article. Clinical Trial.
Acute promyelocytic leukemia.
Warrell RP Jr, de Thé H, Wang ZY, Degos L. Warrell RP Jr, et al. Among authors: de the h. N Engl J Med. 1993 Jul 15;329(3):177-89. doi: 10.1056/NEJM199307153290307. N Engl J Med. 1993. PMID: 8515790 Review.
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells.
Chen GQ, Shi XG, Tang W, Xiong SM, Zhu J, Cai X, Han ZG, Ni JH, Shi GY, Jia PM, Liu MM, He KL, Niu C, Ma J, Zhang P, Zhang TD, Paul P, Naoe T, Kitamura K, Miller W, Waxman S, Wang ZY, de The H, Chen SJ, Chen Z. Chen GQ, et al. Among authors: de the h. Blood. 1997 May 1;89(9):3345-53. Blood. 1997. PMID: 9129041 Free article.
Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies.
Koken MH, Reid A, Quignon F, Chelbi-Alix MK, Davies JM, Kabarowski JH, Zhu J, Dong S, Chen S, Chen Z, Tan CC, Licht J, Waxman S, de Thé H, Zelent A. Koken MH, et al. Among authors: de the h. Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10255-60. doi: 10.1073/pnas.94.19.10255. Proc Natl Acad Sci U S A. 1997. PMID: 9294197 Free PMC article.
How acute promyelocytic leukaemia revived arsenic.
Zhu J, Chen Z, Lallemand-Breitenbach V, de Thé H. Zhu J, et al. Among authors: de the h. Nat Rev Cancer. 2002 Sep;2(9):705-13. doi: 10.1038/nrc887. Nat Rev Cancer. 2002. PMID: 12209159 Review.
286 results