Giaccia AJ - Search Results

1

Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice.

Bedogni B, O'Neill MS, Welford SM, Bouley DM, Giaccia AJ, Denko NC, Powell MB. Bedogni B, et al. Among authors: giaccia aj. Cancer Res. 2004 Apr 1;64(7):2552-60. doi: 10.1158/0008-5472.can-03-3327. Cancer Res. 2004. PMID: 15059911

2

Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment.

Papandreou I, Krishna C, Kaper F, Cai D, Giaccia AJ, Denko NC. Papandreou I, et al. Among authors: giaccia aj. Cancer Res. 2005 Apr 15;65(8):3171-8. doi: 10.1158/0008-5472.CAN-04-3395. Cancer Res. 2005. PMID: 15833847

3

The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.

Bedogni B, Welford SM, Cassarino DS, Nickoloff BJ, Giaccia AJ, Powell MB. Bedogni B, et al. Among authors: giaccia aj. Cancer Cell. 2005 Dec;8(6):443-54. doi: 10.1016/j.ccr.2005.11.005. Cancer Cell. 2005. PMID: 16338658 Free article.

4

Notch1 is an effector of Akt and hypoxia in melanoma development.

Bedogni B, Warneke JA, Nickoloff BJ, Giaccia AJ, Powell MB. Bedogni B, et al. Among authors: giaccia aj. J Clin Invest. 2008 Nov;118(11):3660-70. doi: 10.1172/JCI36157. Epub 2008 Oct 16. J Clin Invest. 2008. PMID: 18924608 Free PMC article.

5

Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2).

Koong AC, Chen EY, Mivechi NF, Denko NC, Stambrook P, Giaccia AJ. Koong AC, et al. Among authors: giaccia aj. Cancer Res. 1994 Oct 15;54(20):5273-9. Cancer Res. 1994. PMID: 7923153

6

Tumor hypoxia, the physiological link between Trousseau's syndrome (carcinoma-induced coagulopathy) and metastasis.

Denko NC, Giaccia AJ. Denko NC, et al. Among authors: giaccia aj. Cancer Res. 2001 Feb 1;61(3):795-8. Cancer Res. 2001. PMID: 11221857 Review. No abstract available.

7

Effects of perillyl alcohol on melanoma in the TPras mouse model.

Lluria-Prevatt M, Morreale J, Gregus J, Alberts DS, Kaper F, Giaccia A, Powell MB. Lluria-Prevatt M, et al. Cancer Epidemiol Biomarkers Prev. 2002 Jun;11(6):573-9. Cancer Epidemiol Biomarkers Prev. 2002. PMID: 12050099

8

Hypoxia links ATR and p53 through replication arrest.

Hammond EM, Denko NC, Dorie MJ, Abraham RT, Giaccia AJ. Hammond EM, et al. Among authors: giaccia aj. Mol Cell Biol. 2002 Mar;22(6):1834-43. doi: 10.1128/MCB.22.6.1834-1843.2002. Mol Cell Biol. 2002. PMID: 11865061 Free PMC article.

9

Hypoxic gene expression and metastasis.

Le QT, Denko NC, Giaccia AJ. Le QT, et al. Among authors: giaccia aj. Cancer Metastasis Rev. 2004 Aug-Dec;23(3-4):293-310. doi: 10.1023/B:CANC.0000031768.89246.d7. Cancer Metastasis Rev. 2004. PMID: 15197330 Review.

10

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC. Romero-Ramirez L, et al. Among authors: giaccia aj. Cancer Res. 2004 Sep 1;64(17):5943-7. doi: 10.1158/0008-5472.CAN-04-1606. Cancer Res. 2004. PMID: 15342372

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