Rosenblum J - Search Results

1

Inhibitor focusing: direct selection of drug targets from proteomes using activity-based probes.

Nomanbhoy TK, Rosenblum J, Aban A, Burbaum JJ. Nomanbhoy TK, et al. Among authors: rosenblum j. Assay Drug Dev Technol. 2003 Feb;1(1 Pt 2):137-46. doi: 10.1089/154065803321537854. Assay Drug Dev Technol. 2003. PMID: 15090140

2

Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3β.

Cociorva OM, Li B, Nomanbhoy T, Li Q, Nakamura A, Nakamura K, Nomura M, Okada K, Seto S, Yumoto K, Liyanage M, Zhang MC, Aban A, Leen B, Szardenings AK, Rosenblum JS, Kozarich JW, Kohno Y, Shreder KR. Cociorva OM, et al. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5948-51. doi: 10.1016/j.bmcl.2011.07.073. Epub 2011 Aug 5. Bioorg Med Chem Lett. 2011. PMID: 21873061

3

Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe.

Okerberg ES, Brown HE, Minimo L, Alemayehu S, Rosenblum J, Patricelli M, Nomanbhoy T, Kozarich JW. Okerberg ES, et al. Among authors: rosenblum j. J Am Chem Soc. 2014 Mar 26;136(12):4664-9. doi: 10.1021/ja4129907. Epub 2014 Mar 17. J Am Chem Soc. 2014. PMID: 24601623

4

Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors.

Shreder KR, Wong MS, Corral S, Yu Z, Winn DT, Wu M, Hu Y, Nomanbhoy T, Alemayehu S, Fuller SR, Rosenblum JS, Kozarich JW. Shreder KR, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4256-60. doi: 10.1016/j.bmcl.2005.06.076. Bioorg Med Chem Lett. 2005. PMID: 16084722

5

Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7.

Hu Y, Ma L, Wu M, Wong MS, Li B, Corral S, Yu Z, Nomanbhoy T, Alemayehu S, Fuller SR, Rosenblum JS, Rozenkrants N, Minimo LC, Ripka WC, Szardenings AK, Kozarich JW, Shreder KR. Hu Y, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4239-42. doi: 10.1016/j.bmcl.2005.06.075. Bioorg Med Chem Lett. 2005. PMID: 16085416

6

Functional interrogation of kinases and other nucleotide-binding proteins.

Rosenblum JS, Nomanbhoy TK, Kozarich JW. Rosenblum JS, et al. FEBS Lett. 2013 Jun 27;587(13):1870-7. doi: 10.1016/j.febslet.2013.05.008. Epub 2013 May 15. FEBS Lett. 2013. PMID: 23684650 Free article. Review.

7

Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response.

Nomanbhoy TK, Sharma G, Brown H, Wu J, Aban A, Vogeti S, Alemayehu S, Sykes M, Rosenblum JS, Kozarich JW. Nomanbhoy TK, et al. Among authors: rosenblum js. Biochemistry. 2016 Sep 27;55(38):5434-41. doi: 10.1021/acs.biochem.6b00629. Epub 2016 Sep 13. Biochemistry. 2016. PMID: 27571378

8

ERK5 kinase activity is dispensable for cellular immune response and proliferation.

Lin EC, Amantea CM, Nomanbhoy TK, Weissig H, Ishiyama J, Hu Y, Sidique S, Li B, Kozarich JW, Rosenblum JS. Lin EC, et al. Among authors: rosenblum js. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11865-11870. doi: 10.1073/pnas.1609019113. Epub 2016 Sep 27. Proc Natl Acad Sci U S A. 2016. PMID: 27679845 Free PMC article.

9

Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast.

Baxter SM, Rosenblum JS, Knutson S, Nelson MR, Montimurro JS, Di Gennaro JA, Speir JA, Burbaum JJ, Fetrow JS. Baxter SM, et al. Among authors: rosenblum js. Mol Cell Proteomics. 2004 Mar;3(3):209-25. doi: 10.1074/mcp.M300082-MCP200. Epub 2003 Nov 25. Mol Cell Proteomics. 2004. PMID: 14645503 Free article.

10

Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.

Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS. Okerberg ES, et al. Among authors: rosenblum js. PLoS One. 2016 Mar 31;11(3):e0152934. doi: 10.1371/journal.pone.0152934. eCollection 2016. PLoS One. 2016. PMID: 27031502 Free PMC article.

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