Fischer PA - Search Results

1

A beta-lactamase-dependent Gal4-estrogen receptor beta transactivation assay for the ultra-high throughput screening of estrogen receptor beta agonists in a 3456-well format.

Peekhaus NT, Ferrer M, Chang T, Kornienko O, Schneeweis JE, Smith TS, Hoffman I, Mitnaul LJ, Chin J, Fischer PA, Blizzard TA, Birzin ET, Chan W, Inglese J, Strulovici B, Rohrer SP, Schaeffer JM. Peekhaus NT, et al. Among authors: fischer pa. Assay Drug Dev Technol. 2003 Dec;1(6):789-800. doi: 10.1089/154065803772613426. Assay Drug Dev Technol. 2003. PMID: 15090225

2

Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors.

Chin J, Adams AD, Bouffard A, Green A, Lacson RG, Smith T, Fischer PA, Menke JG, Sparrow CP, Mitnaul LJ. Chin J, et al. Among authors: fischer pa. Assay Drug Dev Technol. 2003 Dec;1(6):777-87. doi: 10.1089/154065803772613417. Assay Drug Dev Technol. 2003. PMID: 15090224

3

A short-incubation reporter-gene assay for high-throughput screening of estrogen receptor-alpha antagonists.

Shi X, Zheng W, Schneeweis JE, Fischer PA, Strulovici B, Peekhaus NT. Shi X, et al. Among authors: fischer pa. Assay Drug Dev Technol. 2005 Aug;3(4):393-400. doi: 10.1089/adt.2005.3.393. Assay Drug Dev Technol. 2005. PMID: 16180994

4

Development of a novel GLUT4 translocation assay for identifying potential novel therapeutic targets for insulin sensitization.

Liu F, Dallas-Yang Q, Castriota G, Fischer P, Santini F, Ferrer M, Li J, Akiyama TE, Berger JP, Zhang BB, Jiang G. Liu F, et al. Biochem J. 2009 Mar 1;418(2):413-20. doi: 10.1042/BJ20082051. Biochem J. 2009. PMID: 19035854

5

Identification of Leu276 of the S1P1 receptor and Phe263 of the S1P3 receptor in interaction with receptor specific agonists by molecular modeling, site-directed mutagenesis, and affinity studies.

Deng Q, Clemas JA, Chrebet G, Fischer P, Hale JJ, Li Z, Mills SG, Bergstrom J, Mandala S, Mosley R, Parent SA. Deng Q, et al. Mol Pharmacol. 2007 Mar;71(3):724-35. doi: 10.1124/mol.106.029223. Epub 2006 Dec 14. Mol Pharmacol. 2007. PMID: 17170199

6

Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation.

Fisher TS, Lo Surdo P, Pandit S, Mattu M, Santoro JC, Wisniewski D, Cummings RT, Calzetta A, Cubbon RM, Fischer PA, Tarachandani A, De Francesco R, Wright SD, Sparrow CP, Carfi A, Sitlani A. Fisher TS, et al. Among authors: fischer pa. J Biol Chem. 2007 Jul 13;282(28):20502-12. doi: 10.1074/jbc.M701634200. Epub 2007 May 10. J Biol Chem. 2007. PMID: 17493938 Free article.

7

Arginine 206 of the C5a receptor is critical for ligand recognition and receptor activation by C-terminal hexapeptide analogs.

DeMartino JA, Konteatis ZD, Siciliano SJ, Van Riper G, Underwood DJ, Fischer PA, Springer MS. DeMartino JA, et al. Among authors: fischer pa. J Biol Chem. 1995 Jul 7;270(27):15966-9. doi: 10.1074/jbc.270.27.15966. J Biol Chem. 1995. PMID: 7608153 Free article.

8

Characterization and species distribution of high affinity GTP-coupled receptors for human rantes and monocyte chemoattractant protein 1.

Van Riper G, Siciliano S, Fischer PA, Meurer R, Springer MS, Rosen H. Van Riper G, et al. Among authors: fischer pa. J Exp Med. 1993 Mar 1;177(3):851-6. doi: 10.1084/jem.177.3.851. J Exp Med. 1993. PMID: 7679712 Free PMC article.

9

Characterization of alpha(4)beta(1) (CD49d/CD29) on equine leukocytes: potential utility of a potent alpha(4)beta(1) (CD49d/CD29) receptor antagonist in the treatment of equine heaves (recurrent airway obstruction).

Treonze KM, Alves K, Fischer P, Hagmann WK, Hora D, Kulick A, Vakerich K, Smith ND, Lingham RB, Maniar S, Reger TS, Zunic J, Munoz B, Prasit P, Nicholson D, Si Q, Judd K, Nicolich S, Kellerhouse P, Thompson D, Mumford RA. Treonze KM, et al. Vet Immunol Immunopathol. 2009 Jul 15;130(1-2):79-87. doi: 10.1016/j.vetimm.2009.01.011. Epub 2009 Feb 4. Vet Immunol Immunopathol. 2009. PMID: 19250687

10

Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation.

Lin CS, Boltz RC, Blake JT, Nguyen M, Talento A, Fischer PA, Springer MS, Sigal NH, Slaughter RS, Garcia ML, et al. Lin CS, et al. Among authors: fischer pa. J Exp Med. 1993 Mar 1;177(3):637-45. doi: 10.1084/jem.177.3.637. J Exp Med. 1993. PMID: 7679705 Free PMC article.

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