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Balance between PGD synthase and PGE synthase is a major determinant of atherosclerotic plaque instability in humans.
Cipollone F, Fazia M, Iezzi A, Ciabattoni G, Pini B, Cuccurullo C, Ucchino S, Spigonardo F, De Luca M, Prontera C, Chiarelli F, Cuccurullo F, Mezzetti A. Cipollone F, et al. Among authors: chiarelli f. Arterioscler Thromb Vasc Biol. 2004 Jul;24(7):1259-65. doi: 10.1161/01.ATV.0000133192.39901.be. Epub 2004 May 20. Arterioscler Thromb Vasc Biol. 2004. PMID: 15155382 Retracted.
Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)-dependent plaque instability.
Cipollone F, Prontera C, Pini B, Marini M, Fazia M, De Cesare D, Iezzi A, Ucchino S, Boccoli G, Saba V, Chiarelli F, Cuccurullo F, Mezzetti A. Cipollone F, et al. Among authors: chiarelli f. Circulation. 2001 Aug 21;104(8):921-7. doi: 10.1161/hc3401.093152. Circulation. 2001. PMID: 11514380
817 results