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Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis.
Distler O, Distler JH, Scheid A, Acker T, Hirth A, Rethage J, Michel BA, Gay RE, Müller-Ladner U, Matucci-Cerinic M, Plate KH, Gassmann M, Gay S. Distler O, et al. Among authors: acker t. Circ Res. 2004 Jul 9;95(1):109-16. doi: 10.1161/01.RES.0000134644.89917.96. Epub 2004 Jun 3. Circ Res. 2004. PMID: 15178641
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.
Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, Wu Y, Bono F, Devy L, Beck H, Scholz D, Acker T, DiPalma T, Dewerchin M, Noel A, Stalmans I, Barra A, Blacher S, VandenDriessche T, Ponten A, Eriksson U, Plate KH, Foidart JM, Schaper W, Charnock-Jones DS, Hicklin DJ, Herbert JM, Collen D, Persico MG. Carmeliet P, et al. Among authors: acker t. Nat Med. 2001 May;7(5):575-83. doi: 10.1038/87904. Nat Med. 2001. PMID: 11329059 Free article.
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.
Oosthuyse B, Moons L, Storkebaum E, Beck H, Nuyens D, Brusselmans K, Van Dorpe J, Hellings P, Gorselink M, Heymans S, Theilmeier G, Dewerchin M, Laudenbach V, Vermylen P, Raat H, Acker T, Vleminckx V, Van Den Bosch L, Cashman N, Fujisawa H, Drost MR, Sciot R, Bruyninckx F, Hicklin DJ, Ince C, Gressens P, Lupu F, Plate KH, Robberecht W, Herbert JM, Collen D, Carmeliet P. Oosthuyse B, et al. Among authors: acker t. Nat Genet. 2001 Jun;28(2):131-8. doi: 10.1038/88842. Nat Genet. 2001. PMID: 11381259
Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1).
Elvert G, Kappel A, Heidenreich R, Englmeier U, Lanz S, Acker T, Rauter M, Plate K, Sieweke M, Breier G, Flamme I. Elvert G, et al. Among authors: acker t. J Biol Chem. 2003 Feb 28;278(9):7520-30. doi: 10.1074/jbc.M211298200. Epub 2002 Dec 2. J Biol Chem. 2003. PMID: 12464608 Free article.
155 results