Jochemsen AG - Search Results

1

Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity.

Danovi D, Meulmeester E, Pasini D, Migliorini D, Capra M, Frenk R, de Graaf P, Francoz S, Gasparini P, Gobbi A, Helin K, Pelicci PG, Jochemsen AG, Marine JC. Danovi D, et al. Among authors: jochemsen ag. Mol Cell Biol. 2004 Jul;24(13):5835-43. doi: 10.1128/MCB.24.13.5835-5843.2004. Mol Cell Biol. 2004. PMID: 15199139 Free PMC article.

2

How phosphorylation regulates the activity of p53.

Steegenga WT, van der Eb AJ, Jochemsen AG. Steegenga WT, et al. Among authors: jochemsen ag. J Mol Biol. 1996 Oct 25;263(2):103-13. doi: 10.1006/jmbi.1996.0560. J Mol Biol. 1996. PMID: 8913292 Review.

3

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms.

Stad R, Little NA, Xirodimas DP, Frenk R, van der Eb AJ, Lane DP, Saville MK, Jochemsen AG. Stad R, et al. Among authors: jochemsen ag. EMBO Rep. 2001 Nov;2(11):1029-34. doi: 10.1093/embo-reports/kve227. Epub 2001 Oct 17. EMBO Rep. 2001. PMID: 11606419 Free PMC article.

4

Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.

Migliorini D, Lazzerini Denchi E, Danovi D, Jochemsen A, Capillo M, Gobbi A, Helin K, Pelicci PG, Marine JC. Migliorini D, et al. Mol Cell Biol. 2002 Aug;22(15):5527-38. doi: 10.1128/MCB.22.15.5527-5538.2002. Mol Cell Biol. 2002. PMID: 12101245 Free PMC article.

5

Critical role for a central part of Mdm2 in the ubiquitylation of p53.

Meulmeester E, Frenk R, Stad R, de Graaf P, Marine JC, Vousden KH, Jochemsen AG. Meulmeester E, et al. Among authors: jochemsen ag. Mol Cell Biol. 2003 Jul;23(14):4929-38. doi: 10.1128/MCB.23.14.4929-4938.2003. Mol Cell Biol. 2003. PMID: 12832478 Free PMC article.

6

Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2.

de Graaf P, Little NA, Ramos YF, Meulmeester E, Letteboer SJ, Jochemsen AG. de Graaf P, et al. Among authors: jochemsen ag. J Biol Chem. 2003 Oct 3;278(40):38315-24. doi: 10.1074/jbc.M213034200. Epub 2003 Jul 21. J Biol Chem. 2003. PMID: 12874296 Free article.

7

Mdmx and Mdm2: brothers in arms?

Marine JC, Jochemsen AG. Marine JC, et al. Among authors: jochemsen ag. Cell Cycle. 2004 Jul;3(7):900-4. Epub 2004 Jul 2. Cell Cycle. 2004. PMID: 15254433 Review.

8

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.

Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AF, Lehmann WD, Jochemsen AG, Shiloh Y. Pereg Y, et al. Among authors: jochemsen ag. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5056-61. doi: 10.1073/pnas.0408595102. Epub 2005 Mar 23. Proc Natl Acad Sci U S A. 2005. PMID: 15788536 Free PMC article.

9

Mdmx as an essential regulator of p53 activity.

Marine JC, Jochemsen AG. Marine JC, et al. Among authors: jochemsen ag. Biochem Biophys Res Commun. 2005 Jun 10;331(3):750-60. doi: 10.1016/j.bbrc.2005.03.151. Biochem Biophys Res Commun. 2005. PMID: 15865931 Review.

10

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.

Meulmeester E, Maurice MM, Boutell C, Teunisse AF, Ovaa H, Abraham TE, Dirks RW, Jochemsen AG. Meulmeester E, et al. Among authors: jochemsen ag. Mol Cell. 2005 May 27;18(5):565-76. doi: 10.1016/j.molcel.2005.04.024. Mol Cell. 2005. PMID: 15916963 Free article.

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