Coe DM - Search Results

1

The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.

Blanco J, Moore RA, Faehnle CR, Coe DM, Viola RE. Blanco J, et al. Among authors: coe dm. Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1388-95. doi: 10.1107/S0907444904012971. Epub 2004 Jul 21. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15272161

2

Assessing the roles of essential functional groups in the mechanism of homoserine succinyltransferase.

Coe DM, Viola RE. Coe DM, et al. Arch Biochem Biophys. 2007 May 15;461(2):211-8. doi: 10.1016/j.abb.2007.03.004. Epub 2007 Apr 2. Arch Biochem Biophys. 2007. PMID: 17442255

3

Positional identification of variants of Adamts16 linked to inherited hypertension.

Joe B, Saad Y, Dhindaw S, Lee NH, Frank BC, Achinike OH, Luu TV, Gopalakrishnan K, Toland EJ, Farms P, Yerga-Woolwine S, Manickavasagam E, Rapp JP, Garrett MR, Coe D, Apte SS, Rankinen T, Pérusse L, Ehret GB, Ganesh SK, Cooper RS, O'Connor A, Rice T, Weder AB, Chakravarti A, Rao DC, Bouchard C. Joe B, et al. Hum Mol Genet. 2009 Aug 1;18(15):2825-38. doi: 10.1093/hmg/ddp218. Epub 2009 May 7. Hum Mol Genet. 2009. PMID: 19423552 Free PMC article.

4

ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells.

Koo BH, Coe DM, Dixon LJ, Somerville RP, Nelson CM, Wang LW, Young ME, Lindner DJ, Apte SS. Koo BH, et al. Among authors: coe dm. Am J Pathol. 2010 Mar;176(3):1494-504. doi: 10.2353/ajpath.2010.090655. Epub 2010 Jan 21. Am J Pathol. 2010. PMID: 20093484 Free PMC article.

5

Synthesis and Evaluation of Small Molecule Inhibitors of the Androgen Receptor N-Terminal Domain.

Henry MC, Riley CM, Hunter I, Elwood JML, Lopez-Fernandez JD, Minty L, Coe DM, McEwan IJ, Jamieson C. Henry MC, et al. Among authors: coe dm. ACS Med Chem Lett. 2023 Nov 17;14(12):1800-1806. doi: 10.1021/acsmedchemlett.3c00426. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116409 Free PMC article.

6

Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines.

Chan K, Sathyamurthi PS, Queisser MA, Mullin M, Shrives H, Coe DM, Burley GA. Chan K, et al. Among authors: coe dm. Bioconjug Chem. 2023 Nov 15;34(11):2049-2054. doi: 10.1021/acs.bioconjchem.3c00366. Epub 2023 Nov 2. Bioconjug Chem. 2023. PMID: 37917829 Free PMC article.

7

Electrochemical Synthesis of Isoxazolines: Method and Mechanism.

Holman SDL, Wills AG, Fazakerley NJ, Poole DL, Coe DM, Berlouis LA, Reid M. Holman SDL, et al. Among authors: coe dm. Chemistry. 2022 Mar 1;28(13):e202103728. doi: 10.1002/chem.202103728. Epub 2022 Feb 10. Chemistry. 2022. PMID: 35076117 Free PMC article.

8

Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.

Wellaway CR, Baldwin IR, Bamborough P, Barker D, Bartholomew MA, Chung CW, Dümpelfeld B, Evans JP, Fazakerley NJ, Homes P, Keeling SP, Lewell XQ, McNab FW, Morley J, Needham D, Neu M, van Oosterhout AJM, Pal A, Reinhard FBM, Rianjongdee F, Robertson CM, Rowland P, Shah RR, Sherriff EB, Sloan LA, Teague S, Thomas DA, Wellaway N, Wojno-Picon J, Woolven JM, Coe DM. Wellaway CR, et al. Among authors: coe dm. J Med Chem. 2022 Jan 13;65(1):633-664. doi: 10.1021/acs.jmedchem.1c01765. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34928601

9

Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs.

Shah RR, Redmond JM, Mihut A, Menon M, Evans JP, Murphy JA, Bartholomew MA, Coe DM. Shah RR, et al. Among authors: coe dm. Bioorg Med Chem. 2020 Mar 1;28(5):115326. doi: 10.1016/j.bmc.2020.115326. Epub 2020 Jan 23. Bioorg Med Chem. 2020. PMID: 32001089 Free article.

10

Stereoselective Glycosylation of 2-Nitrogalactals Catalyzed by a Bifunctional Organocatalyst.

Medina S, Harper MJ, Balmond EI, Miranda S, Crisenza GE, Coe DM, McGarrigle EM, Galan MC. Medina S, et al. Among authors: coe dm. Org Lett. 2016 Sep 2;18(17):4222-5. doi: 10.1021/acs.orglett.6b01962. Epub 2016 Aug 16. Org Lett. 2016. PMID: 27529800 Free PMC article.

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