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Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.
Oliveira C, Westra JL, Arango D, Ollikainen M, Domingo E, Ferreira A, Velho S, Niessen R, Lagerstedt K, Alhopuro P, Laiho P, Veiga I, Teixeira MR, Ligtenberg M, Kleibeuker JH, Sijmons RH, Plukker JT, Imai K, Lage P, Hamelin R, Albuquerque C, Schwartz S Jr, Lindblom A, Peltomaki P, Yamamoto H, Aaltonen LA, Seruca R, Hofstra RM. Oliveira C, et al. Among authors: alhopuro p. Hum Mol Genet. 2004 Oct 1;13(19):2303-11. doi: 10.1093/hmg/ddh238. Epub 2004 Aug 4. Hum Mol Genet. 2004. PMID: 15294875
SMAD4 as a prognostic marker in colorectal cancer.
Alazzouzi H, Alhopuro P, Salovaara R, Sammalkorpi H, Järvinen H, Mecklin JP, Hemminki A, Schwartz S Jr, Aaltonen LA, Arango D. Alazzouzi H, et al. Among authors: alhopuro p. Clin Cancer Res. 2005 Apr 1;11(7):2606-11. doi: 10.1158/1078-0432.CCR-04-1458. Clin Cancer Res. 2005. PMID: 15814640
Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers.
Hienonen T, Sammalkorpi H, Enholm S, Alhopuro P, Barber TD, Lehtonen R, Nupponen NN, Lehtonen H, Salovaara R, Mecklin JP, Järvinen H, Koistinen R, Arango D, Launonen V, Vogelstein B, Karhu A, Aaltonen LA. Hienonen T, et al. Among authors: alhopuro p. Cancer Res. 2005 Jun 1;65(11):4607-13. doi: 10.1158/0008-5472.CAN-05-0165. Cancer Res. 2005. PMID: 15930278
The MDM2 promoter polymorphism SNP309T-->G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck.
Alhopuro P, Ylisaukko-Oja SK, Koskinen WJ, Bono P, Arola J, Järvinen HJ, Mecklin JP, Atula T, Kontio R, Mäkitie AA, Suominen S, Leivo I, Vahteristo P, Aaltonen LM, Aaltonen LA. Alhopuro P, et al. J Med Genet. 2005 Sep;42(9):694-8. doi: 10.1136/jmg.2005.031260. J Med Genet. 2005. PMID: 16141004 Free PMC article.
Gene-expression profiling predicts recurrence in Dukes' C colorectal cancer.
Arango D, Laiho P, Kokko A, Alhopuro P, Sammalkorpi H, Salovaara R, Nicorici D, Hautaniemi S, Alazzouzi H, Mecklin JP, Järvinen H, Hemminki A, Astola J, Schwartz S Jr, Aaltonen LA. Arango D, et al. Among authors: alhopuro p. Gastroenterology. 2005 Sep;129(3):874-84. doi: 10.1053/j.gastro.2005.06.066. Gastroenterology. 2005. PMID: 16143127
SMAD4 levels and response to 5-fluorouracil in colorectal cancer.
Alhopuro P, Alazzouzi H, Sammalkorpi H, Dávalos V, Salovaara R, Hemminki A, Järvinen H, Mecklin JP, Schwartz S Jr, Aaltonen LA, Arango D. Alhopuro P, et al. Clin Cancer Res. 2005 Sep 1;11(17):6311-6. doi: 10.1158/1078-0432.CCR-05-0244. Clin Cancer Res. 2005. PMID: 16144935
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