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The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition.
Sidobre S, Hammond KJ, Bénazet-Sidobre L, Maltsev SD, Richardson SK, Ndonye RM, Howell AR, Sakai T, Besra GS, Porcelli SA, Kronenberg M. Sidobre S, et al. Among authors: porcelli sa. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12254-9. doi: 10.1073/pnas.0404632101. Epub 2004 Aug 10. Proc Natl Acad Sci U S A. 2004. PMID: 15304644 Free PMC article.
CD1d-restricted T cell activation by nonlipidic small molecules.
Van Rhijn I, Young DC, Im JS, Levery SB, Illarionov PA, Besra GS, Porcelli SA, Gumperz J, Cheng TY, Moody DB. Van Rhijn I, et al. Among authors: porcelli sa. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13578-83. doi: 10.1073/pnas.0402838101. Epub 2004 Sep 1. Proc Natl Acad Sci U S A. 2004. PMID: 15342907 Free PMC article.
Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen.
Patel O, Pellicci DG, Uldrich AP, Sullivan LC, Bhati M, McKnight M, Richardson SK, Howell AR, Mallevaey T, Zhang J, Bedel R, Besra GS, Brooks AG, Kjer-Nielsen L, McCluskey J, Porcelli SA, Gapin L, Rossjohn J, Godfrey DI. Patel O, et al. Among authors: porcelli sa. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19007-12. doi: 10.1073/pnas.1109066108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065767 Free PMC article.
Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation.
Im JS, Arora P, Bricard G, Molano A, Venkataswamy MM, Baine I, Jerud ES, Goldberg MF, Baena A, Yu KO, Ndonye RM, Howell AR, Yuan W, Cresswell P, Chang YT, Illarionov PA, Besra GS, Porcelli SA. Im JS, et al. Among authors: porcelli sa. Immunity. 2009 Jun 19;30(6):888-98. doi: 10.1016/j.immuni.2009.03.022. Immunity. 2009. PMID: 19538930 Free PMC article.
A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.
Lombardi V, Stock P, Singh AK, Kerzerho J, Yang W, Sullivan BA, Li X, Shiratsuchi T, Hnatiuk NE, Howell AR, Yu KO, Porcelli SA, Tsuji M, Kronenberg M, Wilson SB, Akbari O. Lombardi V, et al. Among authors: porcelli sa. J Immunol. 2010 Feb 15;184(4):2107-15. doi: 10.4049/jimmunol.0901208. Epub 2010 Jan 18. J Immunol. 2010. PMID: 20083656 Free PMC article.
Glycolipids that elicit IFN-γ-biased responses from natural killer T cells.
Tyznik AJ, Farber E, Girardi E, Birkholz A, Li Y, Chitale S, So R, Arora P, Khurana A, Wang J, Porcelli SA, Zajonc DM, Kronenberg M, Howell AR. Tyznik AJ, et al. Among authors: porcelli sa. Chem Biol. 2011 Dec 23;18(12):1620-30. doi: 10.1016/j.chembiol.2011.10.015. Chem Biol. 2011. PMID: 22195564 Free PMC article.
287 results