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Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss.
Rüttiger L, Sausbier M, Zimmermann U, Winter H, Braig C, Engel J, Knirsch M, Arntz C, Langer P, Hirt B, Müller M, Köpschall I, Pfister M, Münkner S, Rohbock K, Pfaff I, Rüsch A, Ruth P, Knipper M. Rüttiger L, et al. Among authors: kopschall i. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12922-7. doi: 10.1073/pnas.0402660101. Epub 2004 Aug 24. Proc Natl Acad Sci U S A. 2004. PMID: 15328414 Free PMC article.
BDNF mRNA expression and protein localization are changed in age-related hearing loss.
Rüttiger L, Panford-Walsh R, Schimmang T, Tan J, Zimmermann U, Rohbock K, Köpschall I, Limberger A, Müller M, Fraenzer JT, Cimerman J, Knipper M. Rüttiger L, et al. Among authors: kopschall i. Neurobiol Aging. 2007 Apr;28(4):586-601. doi: 10.1016/j.neurobiolaging.2006.02.008. Epub 2006 Mar 31. Neurobiol Aging. 2007. PMID: 16580094
Thyroid hormone receptors TRalpha1 and TRbeta differentially regulate gene expression of Kcnq4 and prestin during final differentiation of outer hair cells.
Winter H, Braig C, Zimmermann U, Geisler HS, Fränzer JT, Weber T, Ley M, Engel J, Knirsch M, Bauer K, Christ S, Walsh EJ, McGee J, Köpschall I, Rohbock K, Knipper M. Winter H, et al. Among authors: kopschall i. J Cell Sci. 2006 Jul 15;119(Pt 14):2975-84. doi: 10.1242/jcs.03013. Epub 2006 Jun 27. J Cell Sci. 2006. PMID: 16803873
Lack of brain-derived neurotrophic factor hampers inner hair cell synapse physiology, but protects against noise-induced hearing loss.
Zuccotti A, Kuhn S, Johnson SL, Franz C, Singer W, Hecker D, Geisler HS, Köpschall I, Rohbock K, Gutsche K, Dlugaiczyk J, Schick B, Marcotti W, Rüttiger L, Schimmang T, Knipper M. Zuccotti A, et al. Among authors: kopschall i. J Neurosci. 2012 Jun 20;32(25):8545-53. doi: 10.1523/JNEUROSCI.1247-12.2012. J Neurosci. 2012. PMID: 22723694 Free PMC article.
Midazolam reverses salicylate-induced changes in brain-derived neurotrophic factor and arg3.1 expression: implications for tinnitus perception and auditory plasticity.
Panford-Walsh R, Singer W, Rüttiger L, Hadjab S, Tan J, Geisler HS, Zimmermann U, Köpschall I, Rohbock K, Vieljans A, Oestreicher E, Knipper M. Panford-Walsh R, et al. Among authors: kopschall i. Mol Pharmacol. 2008 Sep;74(3):595-604. doi: 10.1124/mol.108.046375. Epub 2008 Jun 4. Mol Pharmacol. 2008. PMID: 18524887
Noise-induced inner hair cell ribbon loss disturbs central arc mobilization: a novel molecular paradigm for understanding tinnitus.
Singer W, Zuccotti A, Jaumann M, Lee SC, Panford-Walsh R, Xiong H, Zimmermann U, Franz C, Geisler HS, Köpschall I, Rohbock K, Varakina K, Verpoorten S, Reinbothe T, Schimmang T, Rüttiger L, Knipper M. Singer W, et al. Among authors: kopschall i. Mol Neurobiol. 2013 Feb;47(1):261-79. doi: 10.1007/s12035-012-8372-8. Epub 2012 Nov 16. Mol Neurobiol. 2013. PMID: 23154938
21 results