Thornton RA - Search Results

1

Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720.

Hale JJ, Yan L, Neway WE, Hajdu R, Bergstrom JD, Milligan JA, Shei GJ, Chrebet GL, Thornton RA, Card D, Rosenbach M, HughRosen, Mandala S. Hale JJ, et al. Among authors: thornton ra. Bioorg Med Chem. 2004 Sep 15;12(18):4803-7. doi: 10.1016/j.bmc.2004.07.020. Bioorg Med Chem. 2004. PMID: 15336258

2

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.

Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, Rosenbach M, Hale J, Lynch CL, Rupprecht K, Parsons W, Rosen H. Mandala S, et al. Science. 2002 Apr 12;296(5566):346-9. doi: 10.1126/science.1070238. Epub 2002 Mar 28. Science. 2002. PMID: 11923495

3

Khafrefungin, a novel inhibitor of sphingolipid synthesis.

Mandala SM, Thornton RA, Rosenbach M, Milligan J, Garcia-Calvo M, Bull HG, Kurtz MB. Mandala SM, et al. Among authors: thornton ra. J Biol Chem. 1997 Dec 19;272(51):32709-14. doi: 10.1074/jbc.272.51.32709. J Biol Chem. 1997. PMID: 9405490 Free article.

4

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death.

Mandala SM, Thornton R, Galve-Roperh I, Poulton S, Peterson C, Olivera A, Bergstrom J, Kurtz MB, Spiegel S. Mandala SM, et al. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7859-64. doi: 10.1073/pnas.120146897. Proc Natl Acad Sci U S A. 2000. PMID: 10859351 Free PMC article.

5

Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase.

Mandala SM, Thornton RA, Milligan J, Rosenbach M, Garcia-Calvo M, Bull HG, Harris G, Abruzzo GK, Flattery AM, Gill CJ, Bartizal K, Dreikorn S, Kurtz MB. Mandala SM, et al. Among authors: thornton ra. J Biol Chem. 1998 Jun 12;273(24):14942-9. doi: 10.1074/jbc.273.24.14942. J Biol Chem. 1998. PMID: 9614099 Free article.

6

Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

Mandala SM, Thornton R, Tu Z, Kurtz MB, Nickels J, Broach J, Menzeleev R, Spiegel S. Mandala SM, et al. Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):150-5. doi: 10.1073/pnas.95.1.150. Proc Natl Acad Sci U S A. 1998. PMID: 9419344 Free PMC article.

7

Viridiofungins, novel inhibitors of sphingolipid synthesis.

Mandala SM, Thornton RA, Frommer BR, Dreikorn S, Kurtz MB. Mandala SM, et al. Among authors: thornton ra. J Antibiot (Tokyo). 1997 Apr;50(4):339-43. doi: 10.7164/antibiotics.50.339. J Antibiot (Tokyo). 1997. PMID: 9186561 Free article.

8

Characterization of murine sphingosine-1-phosphate phosphohydrolase.

Le Stunff H, Peterson C, Thornton R, Milstien S, Mandala SM, Spiegel S. Le Stunff H, et al. J Biol Chem. 2002 Mar 15;277(11):8920-7. doi: 10.1074/jbc.M109968200. Epub 2001 Dec 26. J Biol Chem. 2002. PMID: 11756451 Free article.

9

Inhibition of fungal sphingolipid biosynthesis by rustmicin, galbonolide B and their new 21-hydroxy analogs.

Harris GH, Shafiee A, Cabello MA, Curotto JE, Genilloud O, Göklen KE, Kurtz MB, Rosenbach M, Salmon PM, Thornton RA, Zink DL, Mandala SM. Harris GH, et al. Among authors: thornton ra. J Antibiot (Tokyo). 1998 Sep;51(9):837-44. doi: 10.7164/antibiotics.51.837. J Antibiot (Tokyo). 1998. PMID: 9820234 Free article.

10

Sphingofungins E and F: novel serinepalmitoyl transferase inhibitors from Paecilomyces variotii.

Horn WS, Smith JL, Bills GF, Raghoobar SL, Helms GL, Kurtz MB, Marrinan JA, Frommer BR, Thornton RA, Mandala SM. Horn WS, et al. Among authors: thornton ra. J Antibiot (Tokyo). 1992 Oct;45(10):1692-6. doi: 10.7164/antibiotics.45.1692. J Antibiot (Tokyo). 1992. PMID: 1474000 Free article. No abstract available.

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