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Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist.
Eur J Pharmacol. 2004 Sep 19;499(1-2):77-84. doi: 10.1016/j.ejphar.2004.07.104.
Eur J Pharmacol. 2004.
PMID: 15363953
Discovery of a potent, non-peptide bradykinin B1 receptor antagonist.
Su DS, Markowitz MK, DiPardo RM, Murphy KL, Harrell CM, O'Malley SS, Ransom RW, Chang RS, Ha S, Hess FJ, Pettibone DJ, Mason GS, Boyce S, Freidinger RM, Bock MG.
Su DS, et al. Among authors: markowitz mk.
J Am Chem Soc. 2003 Jun 25;125(25):7516-7. doi: 10.1021/ja0353457.
J Am Chem Soc. 2003.
PMID: 12812482
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Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model.
Hess JF, Ransom RW, Zeng Z, Chang RS, Hey PJ, Warren L, Harrell CM, Murphy KL, Chen TB, Miller PJ, Lis E, Reiss D, Gibson RE, Markowitz MK, DiPardo RM, Su DS, Bock MG, Gould RJ, Pettibone DJ.
Hess JF, et al. Among authors: markowitz mk.
J Pharmacol Exp Ther. 2004 Aug;310(2):488-97. doi: 10.1124/jpet.104.066886. Epub 2004 Mar 29.
J Pharmacol Exp Ther. 2004.
PMID: 15051800
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Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies.
Su DS, Markowitz MK, Murphy KL, Wan BL, Zrada MM, Harrell CM, O'Malley SS, Hess JF, Ransom RW, Chang RS, Wallace MA, Raab CE, Dean DC, Pettibone DJ, Freidinger RM, Bock MG.
Su DS, et al. Among authors: markowitz mk.
Bioorg Med Chem Lett. 2004 Dec 20;14(24):6045-8. doi: 10.1016/j.bmcl.2004.09.074.
Bioorg Med Chem Lett. 2004.
PMID: 15546726
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Binding modes of dihydroquinoxalinones in a homology model of bradykinin receptor 1.
Ha SN, Hey PJ, Ransom RW, Harrell CM Jr, Murphy KL, Chang R, Chen TB, Su DS, Markowitz MK, Bock MG, Freidinger RM, Hess FJ.
Ha SN, et al. Among authors: markowitz mk.
Biochem Biophys Res Commun. 2005 May 27;331(1):159-66. doi: 10.1016/j.bbrc.2005.03.142.
Biochem Biophys Res Commun. 2005.
PMID: 15845373
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Potent bradykinin B1 receptor antagonists: 4-substituted phenyl cyclohexanes.
Su DS, Lim JL, Markowitz MK, Wan BL, Murphy KL, Reiss DR, Harrell CM, O'Malley SS, Ransom RW, Chang RS, Pettibone DJ, Tang C, Prueksaritanont T, Freidinger RM, Bock MG.
Su DS, et al. Among authors: markowitz mk.
Bioorg Med Chem Lett. 2007 Jun 1;17(11):3006-9. doi: 10.1016/j.bmcl.2007.03.059. Epub 2007 Mar 21.
Bioorg Med Chem Lett. 2007.
PMID: 17428657
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Aldosterone receptor antagonists in cardiovascular disease: a review of the recent literature and insight into potential future indications.
Markowitz M, Messineo F, Coplan NL.
Markowitz M, et al.
Clin Cardiol. 2012 Oct;35(10):605-9. doi: 10.1002/clc.22025. Epub 2012 Jul 6.
Clin Cardiol. 2012.
PMID: 22778046
Free PMC article.
Review.
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