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Rho-mediated cytoskeletal rearrangement in response to LPA is functionally antagonized by Rac1 and PIP2.
J Neurochem. 2004 Oct;91(2):501-12. doi: 10.1111/j.1471-4159.2004.02749.x.
J Neurochem. 2004.
PMID: 15447683
Free article.
Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kappaB activation.
Haga JH, Kaunas R, Radeff-Huang J, Weems JM, Estrada KD, Chien S, Brown JH, Seasholtz TM.
Haga JH, et al. Among authors: weems jm.
Biochem Biophys Res Commun. 2008 Jul 18;372(1):216-20. doi: 10.1016/j.bbrc.2008.05.013. Epub 2008 May 12.
Biochem Biophys Res Commun. 2008.
PMID: 18474218
Free PMC article.
Item in Clipboard
KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.
Kelber JA, Reno T, Kaushal S, Metildi C, Wright T, Stoletov K, Weems JM, Park FD, Mose E, Wang Y, Hoffman RM, Lowy AM, Bouvet M, Klemke RL.
Kelber JA, et al. Among authors: weems jm.
Cancer Res. 2012 May 15;72(10):2554-64. doi: 10.1158/0008-5472.CAN-11-3552.
Cancer Res. 2012.
PMID: 22589274
Free PMC article.
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The pharmacodynamic effects of combined administration of flibanserin and alcohol.
Stevens DM, Weems JM, Brown L, Barbour KA, Stahl SM.
Stevens DM, et al. Among authors: weems jm.
J Clin Pharm Ther. 2017 Oct;42(5):598-606. doi: 10.1111/jcpt.12563. Epub 2017 Jun 13.
J Clin Pharm Ther. 2017.
PMID: 28608926
Clinical Trial.
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Potent mutagenicity of 3-methylindole requires pulmonary cytochrome P450-mediated bioactivation: a comparison to the prototype cigarette smoke mutagens B(a)P and NNK.
Weems JM, Lamb JG, D'Agostino J, Ding X, Yost GS.
Weems JM, et al.
Chem Res Toxicol. 2010 Nov 15;23(11):1682-90. doi: 10.1021/tx100147z. Epub 2010 Aug 26.
Chem Res Toxicol. 2010.
PMID: 20795680
Free PMC article.
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3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively.
Weems JM, Yost GS.
Weems JM, et al.
Chem Res Toxicol. 2010 Mar 15;23(3):696-704. doi: 10.1021/tx9004506.
Chem Res Toxicol. 2010.
PMID: 20187624
Free PMC article.
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3-Methylindole is mutagenic and a possible pulmonary carcinogen.
Weems JM, Cutler NS, Moore C, Nichols WK, Martin D, Makin E, Lamb JG, Yost GS.
Weems JM, et al.
Toxicol Sci. 2009 Nov;112(1):59-67. doi: 10.1093/toxsci/kfp201. Epub 2009 Aug 21.
Toxicol Sci. 2009.
PMID: 19700606
Free PMC article.
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