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A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease.
Hovingh GK, Brownlie A, Bisoendial RJ, Dube MP, Levels JH, Petersen W, Dullaart RP, Stroes ES, Zwinderman AH, de Groot E, Hayden MR, Kuivenhoven JA, Kastelein JJ. Hovingh GK, et al. Among authors: kastelein jj. J Am Coll Cardiol. 2004 Oct 6;44(7):1429-35. doi: 10.1016/j.jacc.2004.06.070. J Am Coll Cardiol. 2004. PMID: 15464323 Free article.
Two-year efficacy and safety of simvastatin 80 mg in familial hypercholesterolemia (the Examination of Probands and Relatives in Statin Studies With Familial Hypercholesterolemia [ExPRESS FH]).
de Sauvage Nolting PR, Buirma RJ, Hutten BA, Kastelein JJ; Dutch ExPRESS Investigator Group. de Sauvage Nolting PR, et al. Among authors: kastelein jj. Am J Cardiol. 2002 Jul 15;90(2):181-4. doi: 10.1016/s0002-9149(02)02449-9. Am J Cardiol. 2002. PMID: 12106856 Clinical Trial. No abstract available.
Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol.
Wellington CL, Yang YZ, Zhou S, Clee SM, Tan B, Hirano K, Zwarts K, Kwok A, Gelfer A, Marcil M, Newman S, Roomp K, Singaraja R, Collins J, Zhang LH, Groen AK, Hovingh K, Brownlie A, Tafuri S, Genest J Jr, Kastelein JJ, Hayden MR. Wellington CL, et al. Among authors: kastelein jj. J Lipid Res. 2002 Nov;43(11):1939-49. doi: 10.1194/jlr.m200277-jlr200. J Lipid Res. 2002. PMID: 12401893 Free article.
894 results