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Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.
Zacharatos PV, Gorgoulis VG, Kotsinas A, Manolis EN, Liloglou T, Rassidakis AN, Kanavaros P, Field JD, Halazonetis T, Kittas C. Zacharatos PV, et al. Among authors: kotsinas a. Anticancer Res. 1999 Jan-Feb;19(1A):579-87. Anticancer Res. 1999. PMID: 10226602
Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs).
Gorgoulis VG, Zacharatos P, Kotsinas A, Mariatos G, Liloglou T, Vogiatzi T, Foukas P, Rassidakis G, Garinis G, Ioannides T, Zoumpourlis V, Bramis J, Michail PO, Asimacopoulos PJ, Field JK, Kittas C. Gorgoulis VG, et al. Among authors: kotsinas a. Mol Med. 2000 Mar;6(3):208-37. Mol Med. 2000. PMID: 10965496 Free PMC article.
Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas.
Kotsinas A, Gorgoulis VG, Zacharatos P, Mariatos G, Kokotas S, Liloglou T, Ikonomopoulos J, Zoumpourlis V, Kyroudi A, Field JK, Asimacopoulos PJ, Kittas C. Kotsinas A, et al. Cancer Genet Cytogenet. 2001 Apr 15;126(2):147-54. doi: 10.1016/s0165-4608(00)00407-6. Cancer Genet Cytogenet. 2001. PMID: 11376808
104 results