Tan J - Search Results

1

Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations.

Chen S, Chen L, Tan J, Chen J, Du L, Sun T, Shen J, Chen K, Jiang H, Shen X. Chen S, et al. Among authors: tan j. J Biol Chem. 2005 Jan 7;280(1):164-73. doi: 10.1074/jbc.M408211200. Epub 2004 Oct 26. J Biol Chem. 2005. PMID: 15507456 Free PMC article.

2

pH-dependent conformational flexibility of the SARS-CoV main proteinase (M(pro)) dimer: molecular dynamics simulations and multiple X-ray structure analyses.

Tan J, Verschueren KH, Anand K, Shen J, Yang M, Xu Y, Rao Z, Bigalke J, Heisen B, Mesters JR, Chen K, Shen X, Jiang H, Hilgenfeld R. Tan J, et al. J Mol Biol. 2005 Nov 18;354(1):25-40. doi: 10.1016/j.jmb.2005.09.012. Epub 2005 Sep 23. J Mol Biol. 2005. PMID: 16242152 Free PMC article.

3

Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor.

Liu GX, Tan JZ, Niu CY, Shen JH, Luo XM, Shen X, Chen KX, Jiang HL. Liu GX, et al. Acta Pharmacol Sin. 2006 Jan;27(1):100-10. doi: 10.1111/j.1745-7254.2006.00251.x. Acta Pharmacol Sin. 2006. PMID: 16364216

4

Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives.

Li J, Tan JZ, Chen LL, Zhang J, Shen X, Mei CL, Fu LL, Lin LP, Ding J, Xiong B, Xiong XS, Liu H, Luo XM, Jiang HL. Li J, et al. Among authors: tan jz. Acta Pharmacol Sin. 2006 Sep;27(9):1259-71. doi: 10.1111/j.1745-7254.2006.00437.x. Acta Pharmacol Sin. 2006. PMID: 16923349

5

Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives.

Li HH, Zheng XH, Tan JZ, Chen LL, Liu H, Luo XM, Shen X, Lin LP, Chen KX, Ding J, Jiang HL. Li HH, et al. Among authors: tan jz. Acta Pharmacol Sin. 2007 Jan;28(1):140-52. doi: 10.1111/j.1745-7254.2007.00473.x. Acta Pharmacol Sin. 2007. PMID: 17184594

6

Structure and dynamics of SARS coronavirus main proteinase (Mpro).

Hilgenfeld R, Anand K, Mesters JR, Rao Z, Shen X, Jiang H, Tan J, Verschueren KH. Hilgenfeld R, et al. Among authors: tan j. Adv Exp Med Biol. 2006;581:585-91. doi: 10.1007/978-0-387-33012-9_106. Adv Exp Med Biol. 2006. PMID: 17037602 Free PMC article. No abstract available.

7

Structure-based identification of small molecule compounds targeting cell cyclophilin A with anti-HIV-1 activity.

Chen S, Zhao X, Tan J, Lu H, Qi Z, Huang Q, Zeng X, Zhang M, Jiang S, Jiang H, Yu L. Chen S, et al. Among authors: tan j. Eur J Pharmacol. 2007 Jun 22;565(1-3):54-9. doi: 10.1016/j.ejphar.2007.03.023. Epub 2007 Mar 24. Eur J Pharmacol. 2007. PMID: 17449029 Free PMC article.

8

In vitro pharmacological characterization of TKI-28, a broad-spectrum tyrosine kinase inhibitor with anti-tumor and anti-angiogenic effects.

Guo XN, Zhong L, Tan JZ, Li J, Luo XM, Jiang HL, Nan FJ, Lin LP, Zhang XW, Ding J. Guo XN, et al. Among authors: tan jz. Cancer Biol Ther. 2005 Oct;4(10):1125-32. doi: 10.4161/cbt.4.10.2024. Epub 2005 Oct 15. Cancer Biol Ther. 2005. PMID: 16096368

9

Structural and functional study of D-glucuronyl C5-epimerase.

Qin Y, Ke J, Gu X, Fang J, Wang W, Cong Q, Li J, Tan J, Brunzelle JS, Zhang C, Jiang Y, Melcher K, Li JP, Xu HE, Ding K. Qin Y, et al. Among authors: tan j. J Biol Chem. 2015 Feb 20;290(8):4620-4630. doi: 10.1074/jbc.M114.602201. Epub 2015 Jan 7. J Biol Chem. 2015. PMID: 25568314 Free PMC article.

10

X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85β subunit.

Chen S, Xiao Y, Ponnusamy R, Tan J, Lei J, Hilgenfeld R. Chen S, et al. Among authors: tan j. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1328-33. doi: 10.1107/S1744309111031691. Epub 2011 Oct 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22102226 Free PMC article.

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