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Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.
Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Chan J, Cravchik A, Ross D, Lau K, Kwok S, Chang SY, Catanese J, Sninsky J, White TJ, Hardy J, Powell J, Lovestone S, Morris JC, Thal L, Owen M, Williams J, Goate A, Grupe A. Li Y, et al. Among authors: lau k. Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15688-93. doi: 10.1073/pnas.0403535101. Epub 2004 Oct 26. Proc Natl Acad Sci U S A. 2004. PMID: 15507493 Free PMC article.
Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study.
Li Y, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Lau K, Catanese J, Sninsky J, Nowotny P, Holmans P, Hardy J, Powell J, Lovestone S, Thal L, Owen M, Williams J, Goate A, Grupe A. Li Y, et al. Among authors: lau k. Neurosci Lett. 2004 Aug 19;366(3):268-71. doi: 10.1016/j.neulet.2004.05.047. Neurosci Lett. 2004. PMID: 15288432
Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.
Li Y, Hollingworth P, Moore P, Foy C, Archer N, Powell J, Nowotny P, Holmans P, O'Donovan M, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Lau K, Cantanese J, Sninsky J, Hardy J, Thal L, Morris JC, Goate A, Lovestone S, Owen M, Williams J, Grupe A. Li Y, et al. Among authors: lau k. Hum Mutat. 2005 Mar;25(3):270-7. doi: 10.1002/humu.20138. Hum Mutat. 2005. PMID: 15714520
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, Al-Saraj S, Killick R, Pickering-Brown S, Moore P, Hollingworth P, Archer N, Foy C, Walter S, Lendon C, Iwatsubo T, Morris JC, Norton J, Mann D, Janssens B, Hardy J, O'Donovan M, Jones L, Williams J, Holmans P, Owen MJ, Grupe A, Powell J, van Hengel J, Goate A, Van Roy F, Lovestone S. Busby V, et al. Neuromolecular Med. 2004;5(2):133-46. doi: 10.1385/NMM:5:2:133. Neuromolecular Med. 2004. PMID: 15075440
Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.
Tutt A, Wang A, Rowland C, Gillett C, Lau K, Chew K, Dai H, Kwok S, Ryder K, Shu H, Springall R, Cane P, McCallie B, Kam-Morgan L, Anderson S, Buerger H, Gray J, Bennington J, Esserman L, Hastie T, Broder S, Sninsky J, Brandt B, Waldman F. Tutt A, et al. Among authors: lau k. BMC Cancer. 2008 Nov 21;8:339. doi: 10.1186/1471-2407-8-339. BMC Cancer. 2008. PMID: 19025599 Free PMC article.
INTERLEUKIN 13 PROMOTES MATURATION AND PROLIFERATION IN METAPLASTIC GASTROIDS.
Contreras-Panta EW, Lee SH, Won Y, Norlander AE, Simmons AJ, Peebles RS Jr, Lau KS, Choi E, Goldenring JR. Contreras-Panta EW, et al. Among authors: lau ks. Cell Mol Gastroenterol Hepatol. 2024 May 28:101366. doi: 10.1016/j.jcmgh.2024.101366. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38815928 Free article.
Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins.
Petruzzella A, Bruand M, Santamaria-Martínez A, Katanayeva N, Reymond L, Wehrle S, Georgeon S, Inel D, van Dalen FJ, Viertl D, Lau K, Pojer F, Schottelius M, Zoete V, Verdoes M, Arber C, Correia BE, Oricchio E. Petruzzella A, et al. Among authors: lau k. Nat Chem Biol. 2024 May 29. doi: 10.1038/s41589-024-01627-z. Online ahead of print. Nat Chem Biol. 2024. PMID: 38811854
Clinical immunogenicity outcomes from GENEr8-1, a phase 3 study of valoctocogene roxaparvovec, an AAV5-vectored gene therapy for hemophilia A.
Long BR, Robinson TM, Day JRS, Yu H, Lau K, Imtiaz U, Patton KS, de Hart G, Henshaw J, Agarwal S, Vettermann C, Zoog SJ, Gupta S. Long BR, et al. Among authors: lau k. Mol Ther. 2024 May 24:S1525-0016(24)00335-6. doi: 10.1016/j.ymthe.2024.05.033. Online ahead of print. Mol Ther. 2024. PMID: 38796703 Free article.
2,917 results