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Page 1
Benzodiazepines as potent and selective bradykinin B1 antagonists.
Wood MR, Kim JJ, Han W, Dorsey BD, Homnick CF, DiPardo RM, Kuduk SD, MacNeil T, Murphy KL, Lis EV, Ransom RW, Stump GL, Lynch JJ, O'Malley SS, Miller PJ, Chen TB, Harrell CM, Chang RS, Sandhu P, Ellis JD, Bondiskey PJ, Pettibone DJ, Freidinger RM, Bock MG. Wood MR, et al. Among authors: chang rs. J Med Chem. 2003 May 8;46(10):1803-6. doi: 10.1021/jm034020y. J Med Chem. 2003. PMID: 12723943
Discovery of a potent, non-peptide bradykinin B1 receptor antagonist.
Su DS, Markowitz MK, DiPardo RM, Murphy KL, Harrell CM, O'Malley SS, Ransom RW, Chang RS, Ha S, Hess FJ, Pettibone DJ, Mason GS, Boyce S, Freidinger RM, Bock MG. Su DS, et al. Among authors: chang rs. J Am Chem Soc. 2003 Jun 25;125(25):7516-7. doi: 10.1021/ja0353457. J Am Chem Soc. 2003. PMID: 12812482
Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model.
Hess JF, Ransom RW, Zeng Z, Chang RS, Hey PJ, Warren L, Harrell CM, Murphy KL, Chen TB, Miller PJ, Lis E, Reiss D, Gibson RE, Markowitz MK, DiPardo RM, Su DS, Bock MG, Gould RJ, Pettibone DJ. Hess JF, et al. Among authors: chang rs. J Pharmacol Exp Ther. 2004 Aug;310(2):488-97. doi: 10.1124/jpet.104.066886. Epub 2004 Mar 29. J Pharmacol Exp Ther. 2004. PMID: 15051800
Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist.
Ransom RW, Harrell CM, Reiss DR, Murphy KL, Chang RS, Hess JF, Miller PJ, O'Malley SS, Hey PJ, Kunapuli P, Su DS, Markowitz MK, Wallace MA, Raab CE, Jones AN, Dean DC, Pettibone DJ, Freidinger RM, Bock MG. Ransom RW, et al. Among authors: chang rs. Eur J Pharmacol. 2004 Sep 19;499(1-2):77-84. doi: 10.1016/j.ejphar.2004.07.104. Eur J Pharmacol. 2004. PMID: 15363953
2,3-diaminopyridine bradykinin B1 receptor antagonists.
Kuduk SD, Ng C, Feng DM, Wai JM, Chang RS, Harrell CM, Murphy KL, Ransom RW, Reiss D, Ivarsson M, Mason G, Boyce S, Tang C, Prueksaritanont T, Freidinger RM, Pettibone DJ, Bock MG. Kuduk SD, et al. Among authors: chang rs. J Med Chem. 2004 Dec 16;47(26):6439-42. doi: 10.1021/jm049394l. J Med Chem. 2004. PMID: 15588075
Cyclopropylamino acid amide as a pharmacophoric replacement for 2,3-diaminopyridine. Application to the design of novel bradykinin B1 receptor antagonists.
Wood MR, Schirripa KM, Kim JJ, Wan BL, Murphy KL, Ransom RW, Chang RS, Tang C, Prueksaritanont T, Detwiler TJ, Hettrick LA, Landis ER, Leonard YM, Krueger JA, Lewis SD, Pettibone DJ, Freidinger RM, Bock MG. Wood MR, et al. Among authors: chang rs. J Med Chem. 2006 Feb 23;49(4):1231-4. doi: 10.1021/jm0511280. J Med Chem. 2006. PMID: 16480259
348 results