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Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.
Gerwin BI, Spillare E, Forrester K, Lehman TA, Kispert J, Welsh JA, Pfeifer AM, Lechner JF, Baker SJ, Vogelstein B, et al. Gerwin BI, et al. Among authors: welsh ja. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2759-63. doi: 10.1073/pnas.89.7.2759. Proc Natl Acad Sci U S A. 1992. PMID: 1557382 Free PMC article.
p53 and Kirsten-ras mutations in human mesothelioma cell lines.
Metcalf RA, Welsh JA, Bennett WP, Seddon MB, Lehman TA, Pelin K, Linnainmaa K, Tammilehto L, Mattson K, Gerwin BI, et al. Metcalf RA, et al. Among authors: welsh ja. Cancer Res. 1992 May 1;52(9):2610-5. Cancer Res. 1992. PMID: 1568228
p53 mutations in human immortalized epithelial cell lines.
Lehman TA, Modali R, Boukamp P, Stanek J, Bennett WP, Welsh JA, Metcalf RA, Stampfer MR, Fusenig N, Rogan EM, et al. Lehman TA, et al. Among authors: welsh ja. Carcinogenesis. 1993 May;14(5):833-9. doi: 10.1093/carcin/14.5.833. Carcinogenesis. 1993. PMID: 8504475
Frequent mutation of the p53 gene in human esophageal cancer.
Hollstein MC, Metcalf RA, Welsh JA, Montesano R, Harris CC. Hollstein MC, et al. Among authors: welsh ja. Proc Natl Acad Sci U S A. 1990 Dec;87(24):9958-61. doi: 10.1073/pnas.87.24.9958. Proc Natl Acad Sci U S A. 1990. PMID: 2263646 Free PMC article.
187 results