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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.
Genes Dev. 2004 Dec 15;18(24):3066-77. doi: 10.1101/gad.1250704.
Genes Dev. 2004.
PMID: 15601821
Free PMC article.
Stress-induced gene expression requires programmed recovery from translational repression.
Novoa I, Zhang Y, Zeng H, Jungreis R, Harding HP, Ron D.
Novoa I, et al. Among authors: jungreis r.
EMBO J. 2003 Mar 3;22(5):1180-7. doi: 10.1093/emboj/cdg112.
EMBO J. 2003.
PMID: 12606582
Free PMC article.
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Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice.
Bertolotti A, Wang X, Novoa I, Jungreis R, Schlessinger K, Cho JH, West AB, Ron D.
Bertolotti A, et al. Among authors: jungreis r.
J Clin Invest. 2001 Mar;107(5):585-93. doi: 10.1172/JCI11476.
J Clin Invest. 2001.
PMID: 11238559
Free PMC article.
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IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.
Iqbal J, Dai K, Seimon T, Jungreis R, Oyadomari M, Kuriakose G, Ron D, Tabas I, Hussain MM.
Iqbal J, et al. Among authors: jungreis r.
Cell Metab. 2008 May;7(5):445-55. doi: 10.1016/j.cmet.2008.03.005.
Cell Metab. 2008.
PMID: 18460335
Free PMC article.
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