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Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders.
Rastan S, Hough T, Kierman A, Hardisty R, Erven A, Gray IC, Voeling S, Isaacs A, Tsai H, Strivens M, Washbourne R, Thornton C, Greenaway S, Hewitt M, McCormick S, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Mburu P, Rogers D, Hagan J, Reavill C, Davies K, Glenister P, Fisher EM, Martin J, Vizor L, Bouzyk M, Kelsell D, Guenet JL, Steel KP, Sheardown S, Spurr N, Gray I, Peters J, Nolan PM, Hunter AJ, Brown SD. Rastan S, et al. Among authors: hardisty r. Genetica. 2004 Sep;122(1):47-9. doi: 10.1007/s10709-004-1930-x. Genetica. 2004. PMID: 15619960
The deaf mouse mutant Jeff (Jf) is a single gene model of otitis media.
Hardisty RE, Erven A, Logan K, Morse S, Guionaud S, Sancho-Oliver S, Hunter AJ, Brown SD, Steel KP. Hardisty RE, et al. J Assoc Res Otolaryngol. 2003 Jun;4(2):130-8. doi: 10.1007/s10162-002-3015-9. J Assoc Res Otolaryngol. 2003. PMID: 12943368 Free PMC article.
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.
Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson JA, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet JL, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher EM, Martin J, Rastan S, Brown SD, Hunter J. Nolan PM, et al. Among authors: hardisty r. Nat Genet. 2000 Aug;25(4):440-3. doi: 10.1038/78140. Nat Genet. 2000. PMID: 10932191
In search of new disease models in the mouse using ENU mutagenesis.
Thaung C, Hough T, Hunter AJ, Hardisty R, Nolan PM. Thaung C, et al. Among authors: hardisty r. Ernst Schering Res Found Workshop. 2002;(36):109-34. doi: 10.1007/978-3-662-04667-8_7. Ernst Schering Res Found Workshop. 2002. PMID: 11859561 No abstract available.
Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31.
Mburu P, Mustapha M, Varela A, Weil D, El-Amraoui A, Holme RH, Rump A, Hardisty RE, Blanchard S, Coimbra RS, Perfettini I, Parkinson N, Mallon AM, Glenister P, Rogers MJ, Paige AJ, Moir L, Clay J, Rosenthal A, Liu XZ, Blanco G, Steel KP, Petit C, Brown SD. Mburu P, et al. Among authors: hardisty re. Nat Genet. 2003 Aug;34(4):421-8. doi: 10.1038/ng1208. Nat Genet. 2003. PMID: 12833159
A radiation hybrid map of mouse genes.
Hudson TJ, Church DM, Greenaway S, Nguyen H, Cook A, Steen RG, Van Etten WJ, Castle AB, Strivens MA, Trickett P, Heuston C, Davison C, Southwell A, Hardisty R, Varela-Carver A, Haynes AR, Rodriguez-Tome P, Doi H, Ko MS, Pontius J, Schriml L, Wagner L, Maglott D, Brown SD, Lander ES, Schuler G, Denny P. Hudson TJ, et al. Among authors: hardisty r. Nat Genet. 2001 Oct;29(2):201-5. doi: 10.1038/ng1001-201. Nat Genet. 2001. PMID: 11586302
156 results