Tomlinson IP - Search Results

1

Clinical features of multiple cutaneous and uterine leiomyomatosis: an underdiagnosed tumor syndrome.

Alam NA, Barclay E, Rowan AJ, Tyrer JP, Calonje E, Manek S, Kelsell D, Leigh I, Olpin S, Tomlinson IP. Alam NA, et al. Among authors: tomlinson ip. Arch Dermatol. 2005 Feb;141(2):199-206. doi: 10.1001/archderm.141.2.199. Arch Dermatol. 2005. PMID: 15724016

2

Beta-catenin mutations in cell lines established from human colorectal cancers.

Ilyas M, Tomlinson IP, Rowan A, Pignatelli M, Bodmer WF. Ilyas M, et al. Among authors: tomlinson ip. Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10330-4. doi: 10.1073/pnas.94.19.10330. Proc Natl Acad Sci U S A. 1997. PMID: 9294210 Free PMC article.

3

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.

Homfray TF, Cottrell SE, Ilyas M, Rowan A, Talbot IC, Bodmer WF, Tomlinson IP. Homfray TF, et al. Among authors: tomlinson ip. Hum Mutat. 1998;11(2):114-20. doi: 10.1002/(SICI)1098-1004(1998)11:2<114::AID-HUMU3>3.0.CO;2-J. Hum Mutat. 1998. PMID: 9482574

4

Genetic aberrations in glioblastoma multiforme: translocation of chromosome 10 in an O-2A-like cell line.

Mao X, Jones TA, Tomlinson I, Rowan AJ, Fedorova LI, Zelenin AV, Mao JI, Gutowski NJ, Noble M, Sheer D. Mao X, et al. Br J Cancer. 1999 Feb;79(5-6):724-31. doi: 10.1038/sj.bjc.6690116. Br J Cancer. 1999. PMID: 10070860 Free PMC article.

5

Somatic mutations in the Peutz-Jeghers (LKB1/STKII) gene in sporadic malignant melanomas.

Rowan A, Bataille V, MacKie R, Healy E, Bicknell D, Bodmer W, Tomlinson I. Rowan A, et al. J Invest Dermatol. 1999 Apr;112(4):509-11. doi: 10.1046/j.1523-1747.1999.00551.x. J Invest Dermatol. 1999. PMID: 10201537 Free article.

6

Mutations in Bcl10 are very rare in colorectal cancer.

Stone JG, Rowan AJ, Tomlinson IP, Houlston RS. Stone JG, et al. Among authors: tomlinson ip. Br J Cancer. 1999 Jul;80(10):1569-70. doi: 10.1038/sj.bjc.6690562. Br J Cancer. 1999. PMID: 10408399 Free PMC article.

7

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.

Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, Frayling I, Efstathiou J, Pack K, Payne S, Roylance R, Gorman P, Sheer D, Neale K, Phillips R, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Nat Med. 1999 Sep;5(9):1071-5. doi: 10.1038/12511. Nat Med. 1999. PMID: 10470088

8

APC mutations are sufficient for the growth of early colorectal adenomas.

Lamlum H, Papadopoulou A, Ilyas M, Rowan A, Gillet C, Hanby A, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2225-8. doi: 10.1073/pnas.040564697. Proc Natl Acad Sci U S A. 2000. PMID: 10681434 Free PMC article.

9

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".

Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP. Rowan AJ, et al. Among authors: tomlinson ip. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3352-7. doi: 10.1073/pnas.97.7.3352. Proc Natl Acad Sci U S A. 2000. PMID: 10737795 Free PMC article.

10

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q.

Lamlum H, Al Tassan N, Jaeger E, Frayling I, Sieber O, Reza FB, Eckert M, Rowan A, Barclay E, Atkin W, Williams C, Gilbert J, Cheadle J, Bell J, Houlston R, Bodmer W, Sampson J, Tomlinson I. Lamlum H, et al. Hum Mol Genet. 2000 Sep 22;9(15):2215-21. doi: 10.1093/oxfordjournals.hmg.a018912. Hum Mol Genet. 2000. PMID: 11001924

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