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Synthesis of the blood circulating C-terminal fragment of insulin-like growth factor (IGF)-binding protein-4 in its native conformation. Crystallization, heparin and IGF binding, and osteogenic activity.
Fernández-Tornero C, Lozano RM, Rivas G, Jiménez MA, Ständker L, Díaz-Gonzalez D, Forssmann WG, Cuevas P, Romero A, Giménez-Gallego G. Fernández-Tornero C, et al. J Biol Chem. 2005 May 13;280(19):18899-907. doi: 10.1074/jbc.M500587200. Epub 2005 Feb 26. J Biol Chem. 2005. PMID: 15735305 Free article.
Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate.
Fernández-Tornero C, Lozano RM, Redondo-Horcajo M, Gómez AM, López JC, Quesada E, Uriel C, Valverde S, Cuevas P, Romero A, Giménez-Gallego G. Fernández-Tornero C, et al. J Biol Chem. 2003 Jun 13;278(24):21774-81. doi: 10.1074/jbc.M212833200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676958 Free article.
38 results