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Synthesis of the blood circulating C-terminal fragment of insulin-like growth factor (IGF)-binding protein-4 in its native conformation. Crystallization, heparin and IGF binding, and osteogenic activity.
Fernández-Tornero C, Lozano RM, Rivas G, Jiménez MA, Ständker L, Díaz-Gonzalez D, Forssmann WG, Cuevas P, Romero A, Giménez-Gallego G. Fernández-Tornero C, et al. J Biol Chem. 2005 May 13;280(19):18899-907. doi: 10.1074/jbc.M500587200. Epub 2005 Feb 26. J Biol Chem. 2005. PMID: 15735305 Free article.
Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate.
Fernández-Tornero C, Lozano RM, Redondo-Horcajo M, Gómez AM, López JC, Quesada E, Uriel C, Valverde S, Cuevas P, Romero A, Giménez-Gallego G. Fernández-Tornero C, et al. J Biol Chem. 2003 Jun 13;278(24):21774-81. doi: 10.1074/jbc.M212833200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676958 Free article.
Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
Fernández IS, Cuevas P, Angulo J, López-Navajas P, Canales-Mayordomo A, González-Corrochano R, Lozano RM, Valverde S, Jiménez-Barbero J, Romero A, Giménez-Gallego G. Fernández IS, et al. J Biol Chem. 2010 Apr 9;285(15):11714-29. doi: 10.1074/jbc.M109.064618. Epub 2010 Feb 9. J Biol Chem. 2010. PMID: 20145243 Free PMC article.
Gene design, expression, crystallization and preliminary diffraction analysis of two isolectins from the fungus Coprinus cinereus: a model for studying functional diversification of galectins in the same organism and their evolutionary pathways.
López-Lucendo MF, Giménez-Gallego G, Cooper DN, Gabius HJ, Romero A. López-Lucendo MF, et al. Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):721-4. doi: 10.1107/S0907444904002008. Epub 2004 Mar 23. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15039565
162 results