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Clinical efficacy of infliximab plus methotrexate in DMARD naive and DMARD refractory rheumatoid arthritis is associated with decreased synovial expression of TNF alpha and IL18 but not CXCL12.
van Oosterhout M, Levarht EW, Sont JK, Huizinga TW, Toes RE, van Laar JM. van Oosterhout M, et al. Among authors: levarht ew. Ann Rheum Dis. 2005 Apr;64(4):537-43. doi: 10.1136/ard.2004.024927. Ann Rheum Dis. 2005. PMID: 15769913 Free PMC article. Clinical Trial.
High dose chemotherapy and syngeneic stem cell transplantation in a patient with refractory rheumatoid arthritis: poor response associated with persistence of host autoantibodies and synovial abnormalities.
van Oosterhout M, Verburg RJ, Levarht EW, Moolenburgh JD, Barge RM, Fibbe WE, van Laar JM. van Oosterhout M, et al. Among authors: levarht ew. Ann Rheum Dis. 2005 Dec;64(12):1783-5. doi: 10.1136/ard.2004.034793. Ann Rheum Dis. 2005. PMID: 16284342 Free PMC article.
Outcome of intensive immunosuppression and autologous stem cell transplantation in patients with severe rheumatoid arthritis is associated with the composition of synovial T cell infiltration.
Verburg RJ, Flierman R, Sont JK, Ponchel F, van Dreunen L, Levarht EW, Welling MM, Toes RE, Isaacs JD, van Laar JM. Verburg RJ, et al. Among authors: levarht ew. Ann Rheum Dis. 2005 Oct;64(10):1397-405. doi: 10.1136/ard.2004.033332. Epub 2005 Apr 13. Ann Rheum Dis. 2005. PMID: 15829573 Free PMC article. Clinical Trial.
Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications.
Kissel T, Reijm S, Slot LM, Cavallari M, Wortel CM, Vergroesen RD, Stoeken-Rijsbergen G, Kwekkeboom JC, Kampstra A, Levarht E, Drijfhout JW, Bang H, Bonger KM, Janssen G, van Veelen PA, Huizinga T, Scherer HU, Reth M, Toes R. Kissel T, et al. Ann Rheum Dis. 2020 Apr;79(4):472-480. doi: 10.1136/annrheumdis-2019-216499. Epub 2020 Feb 10. Ann Rheum Dis. 2020. PMID: 32041746
Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis.
Trouw LA, Daha N, Kurreeman FA, Böhringer S, Goulielmos GN, Westra HJ, Zhernakova A, Franke L, Stahl EA, Levarht EW, Stoeken-Rijsbergen G, Verduijn W, Roos A, Li Y, Houwing-Duistermaat JJ, Huizinga TW, Toes RE. Trouw LA, et al. Among authors: levarht ew. Clin Exp Immunol. 2013 Jul;173(1):76-83. doi: 10.1111/cei.12097. Clin Exp Immunol. 2013. PMID: 23607884 Free PMC article.
Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients.
Muller PC, Anink J, Shi J, Levarht EW, Reinards TH, Otten MH, van Tol MJ, Jol-van der Zijde CM, Brinkman DM, Allaart CF, Hoppenreijs EP, Koopman-Keemink Y, Kamphuis SS, Dolman K, van den Berg JM, van Rossum MA, van Suijlekom-Smit LW, Schilham MW, Huizinga TW, Toes RE, Ten Cate R, Trouw LA. Muller PC, et al. Among authors: levarht ew. Ann Rheum Dis. 2013 Dec;72(12):2053-5. doi: 10.1136/annrheumdis-2013-203650. Epub 2013 Jul 19. Ann Rheum Dis. 2013. PMID: 23873877 No abstract available.
Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation.
Verheul MK, van Erp SJ, van der Woude D, Levarht EW, Mallat MJ, Verspaget HW, Stolk J, Toes RE, van der Meulen-de Jong AE, Hiemstra PS, van Kooten C, Trouw LA. Verheul MK, et al. Among authors: levarht ew. Ann Rheum Dis. 2016 Aug;75(8):1575-6. doi: 10.1136/annrheumdis-2016-209248. Epub 2016 Apr 29. Ann Rheum Dis. 2016. PMID: 27130909 No abstract available.
31 results