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Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of betaII tryptase.
Levell J, Astles P, Eastwood P, Cairns J, Houille O, Aldous S, Merriman G, Whiteley B, Pribish J, Czekaj M, Liang G, Maignan S, Guilloteau JP, Dupuy A, Davidson J, Harrison T, Morley A, Watson S, Fenton G, McCarthy C, Romano J, Mathew R, Engers D, Gardyan M, Sides K, Kwong J, Tsay J, Rebello S, Shen L, Wang J, Luo Y, Giardino O, Lim HK, Smith K, Pauls H. Levell J, et al. Among authors: lim hk. Bioorg Med Chem. 2005 Apr 15;13(8):2859-72. doi: 10.1016/j.bmc.2005.02.014. Bioorg Med Chem. 2005. PMID: 15781396
Design of bivalent ligands using hydrogen bond linkers: synthesis and evaluation of inhibitors for human beta-tryptase.
Vaz RJ, Gao Z, Pribish J, Chen X, Levell J, Davis L, Albert E, Brollo M, Ugolini A, Cramer DM, Cairns J, Sides K, Liu F, Kwong J, Kang J, Rebello S, Elliot M, Lim H, Chellaraj V, Singleton RW, Li Y. Vaz RJ, et al. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6053-6. doi: 10.1016/j.bmcl.2004.09.065. Bioorg Med Chem Lett. 2004. PMID: 15546728
The conduct of in vitro studies to address time-dependent inhibition of drug-metabolizing enzymes: a perspective of the pharmaceutical research and manufacturers of America.
Grimm SW, Einolf HJ, Hall SD, He K, Lim HK, Ling KH, Lu C, Nomeir AA, Seibert E, Skordos KW, Tonn GR, Van Horn R, Wang RW, Wong YN, Yang TJ, Obach RS. Grimm SW, et al. Among authors: lim hk. Drug Metab Dispos. 2009 Jul;37(7):1355-70. doi: 10.1124/dmd.109.026716. Epub 2009 Apr 9. Drug Metab Dispos. 2009. PMID: 19359406
High-Power and Large-Area Anodes for Safe Lithium-Metal Batteries.
Ha S, Park JY, Huh SH, Yu SH, Kwak JH, Park J, Lim HD, Ahn DJ, Jin HJ, Lim HK, Yang SJ, Yun YS. Ha S, et al. Among authors: lim hk. Small. 2024 May 28:e2400638. doi: 10.1002/smll.202400638. Online ahead of print. Small. 2024. PMID: 38804126
1,000 results