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Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3.
Ondeykal JG, Herath KB, Jayasuriya H, Polishook JD, Bills GF, Dombrowski AW, Mojena M, Koch G, DiSalvo J, DeMartino J, Guan Z, Nanakorn W, Morenberg CM, Balick MJ, Stevenson DW, Slattery M, Borris RP, Singh SB. Ondeykal JG, et al. Among authors: mojena m. Mol Divers. 2005;9(1-3):123-9. doi: 10.1007/s11030-005-1296-8. Mol Divers. 2005. PMID: 15789559
Resorcylic acid lactones: naturally occurring potent and selective inhibitors of MEK.
Zhao A, Lee SH, Mojena M, Jenkins RG, Patrick DR, Huber HE, Goetz MA, Hensens OD, Zink DL, Vilella D, Dombrowski AW, Lingham RB, Huang L. Zhao A, et al. Among authors: mojena m. J Antibiot (Tokyo). 1999 Dec;52(12):1086-94. doi: 10.7164/antibiotics.52.1086. J Antibiot (Tokyo). 1999. PMID: 10695671 Free article.
A novel antiviral agent which inhibits the endonuclease of influenza viruses.
Tomassini JE, Davies ME, Hastings JC, Lingham R, Mojena M, Raghoobar SL, Singh SB, Tkacz JS, Goetz MA. Tomassini JE, et al. Among authors: mojena m. Antimicrob Agents Chemother. 1996 May;40(5):1189-93. doi: 10.1128/AAC.40.5.1189. Antimicrob Agents Chemother. 1996. PMID: 8723464 Free PMC article.
Androstenediol analogs as ER-beta-selective SERMs.
Blizzard TA, Gude C, Morgan JD 2nd, Chan W, Birzin ET, Mojena M, Tudela C, Chen F, Knecht K, Su Q, Kraker B, Mosley RT, Holmes MA, Sharma N, Fitzgerald PM, Rohrer SP, Hammond ML. Blizzard TA, et al. Among authors: mojena m. Bioorg Med Chem Lett. 2006 Feb 15;16(4):834-8. doi: 10.1016/j.bmcl.2005.11.014. Epub 2005 Nov 23. Bioorg Med Chem Lett. 2006. PMID: 16309907
Estrogen receptor beta-subtype selective tetrahydrofluorenones: use of a fused pyrazole as a phenol bioisostere.
Wilkening RR, Ratcliffe RW, Fried AK, Meng D, Sun W, Colwell L, Lambert S, Greenlee M, Nilsson S, Thorsell A, Mojena M, Tudela C, Frisch K, Chan W, Birzin ET, Rohrer SP, Hammond ML. Wilkening RR, et al. Among authors: mojena m. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3896-901. doi: 10.1016/j.bmcl.2006.05.036. Epub 2006 May 30. Bioorg Med Chem Lett. 2006. PMID: 16730987
Bridged androstenediol analogs as ER-beta selective SERMs.
Blizzard TA, Gude C, Chan W, Birzin ET, Mojena M, Tudela C, Chen F, Knecht K, Su Q, Kraker B, Holmes MA, Rohrer SP, Hammond ML. Blizzard TA, et al. Among authors: mojena m. Bioorg Med Chem Lett. 2007 May 15;17(10):2944-8. doi: 10.1016/j.bmcl.2006.12.053. Epub 2006 Dec 21. Bioorg Med Chem Lett. 2007. PMID: 17448656
Direct agonist/antagonist functions of dehydroepiandrosterone.
Chen F, Knecht K, Birzin E, Fisher J, Wilkinson H, Mojena M, Moreno CT, Schmidt A, Harada S, Freedman LP, Reszka AA. Chen F, et al. Among authors: mojena m. Endocrinology. 2005 Nov;146(11):4568-76. doi: 10.1210/en.2005-0368. Epub 2005 Jun 30. Endocrinology. 2005. PMID: 15994348
Androstene-3,5-dienes as ER-beta selective SERMs.
Blizzard TA, Gude C, Morgan JD 2nd, Chan W, Birzin ET, Mojena M, Tudela C, Chen F, Knecht K, Su Q, Kraker B, Mosley RT, Holmes MA, Rohrer SP, Hammond ML. Blizzard TA, et al. Among authors: mojena m. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6295-8. doi: 10.1016/j.bmcl.2007.09.001. Epub 2007 Sep 7. Bioorg Med Chem Lett. 2007. PMID: 17890084
44 results