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The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design.
Altfeld M, Allen TM, Kalife ET, Frahm N, Addo MM, Mothe BR, Rathod A, Reyor LL, Harlow J, Yu XG, Perkins B, Robinson LK, Sidney J, Alter G, Lichterfeld M, Sette A, Rosenberg ES, Goulder PJ, Brander C, Walker BD. Altfeld M, et al. Among authors: mothe br. J Virol. 2005 Apr;79(8):5000-5. doi: 10.1128/JVI.79.8.5000-5005.2005. J Virol. 2005. PMID: 15795285 Free PMC article.
Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.
Allen TM, Jing P, Calore B, Horton H, O'Connor DH, Hanke T, Piekarczyk M, Ruddersdorf R, Mothé BR, Emerson C, Wilson N, Lifson JD, Belyakov IM, Berzofsky JA, Wang C, Allison DB, Montefiori DC, Desrosiers RC, Wolinsky S, Kunstman KJ, Altman JD, Sette A, McMichael AJ, Watkins DI. Allen TM, et al. Among authors: mothe br. J Virol. 2002 Oct;76(20):10507-11. doi: 10.1128/jvi.76.20.10507-10511.2002. J Virol. 2002. PMID: 12239328 Free PMC article.
Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.
Allen TM, Altfeld M, Yu XG, O'Sullivan KM, Lichterfeld M, Le Gall S, John M, Mothe BR, Lee PK, Kalife ET, Cohen DE, Freedberg KA, Strick DA, Johnston MN, Sette A, Rosenberg ES, Mallal SA, Goulder PJ, Brander C, Walker BD. Allen TM, et al. Among authors: mothe br. J Virol. 2004 Jul;78(13):7069-78. doi: 10.1128/JVI.78.13.7069-7078.2004. J Virol. 2004. PMID: 15194783 Free PMC article.
T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily.
Lichterfeld M, Williams KL, Mui SK, Shah SS, Mothe BR, Sette A, Kim A, Johnston MN, Burgett N, Frahm N, Cohen D, Brander C, Rosenberg ES, Walker BD, Altfeld M, Yu XG. Lichterfeld M, et al. Among authors: mothe br. Int Immunol. 2006 Jul;18(7):1179-88. doi: 10.1093/intimm/dxl052. Epub 2006 Jun 13. Int Immunol. 2006. PMID: 16772368
Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid.
Schneidewind A, Brockman MA, Sidney J, Wang YE, Chen H, Suscovich TJ, Li B, Adam RI, Allgaier RL, Mothé BR, Kuntzen T, Oniangue-Ndza C, Trocha A, Yu XG, Brander C, Sette A, Walker BD, Allen TM. Schneidewind A, et al. Among authors: mothe br. J Virol. 2008 Jun;82(11):5594-605. doi: 10.1128/JVI.02356-07. Epub 2008 Apr 2. J Virol. 2008. PMID: 18385228 Free PMC article.
Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.
Schulze zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, Allen TM, McGovern B, Lewis-Ximenez L, Sidney J, Sette A, Chung RT, Walker BD. Schulze zur Wiesch J, et al. J Immunol. 2005 Sep 15;175(6):3603-13. doi: 10.4049/jimmunol.175.6.3603. J Immunol. 2005. PMID: 16148104
Identification of protective Lassa virus epitopes that are restricted by HLA-A2.
Botten J, Alexander J, Pasquetto V, Sidney J, Barrowman P, Ting J, Peters B, Southwood S, Stewart B, Rodriguez-Carreno MP, Mothe B, Whitton JL, Sette A, Buchmeier MJ. Botten J, et al. J Virol. 2006 Sep;80(17):8351-61. doi: 10.1128/JVI.00896-06. J Virol. 2006. PMID: 16912286 Free PMC article.
Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.
O'Connor DH, Mothe BR, Weinfurter JT, Fuenger S, Rehrauer WM, Jing P, Rudersdorf RR, Liebl ME, Krebs K, Vasquez J, Dodds E, Loffredo J, Martin S, McDermott AB, Allen TM, Wang C, Doxiadis GG, Montefiori DC, Hughes A, Burton DR, Allison DB, Wolinsky SM, Bontrop R, Picker LJ, Watkins DI. O'Connor DH, et al. Among authors: mothe br. J Virol. 2003 Aug;77(16):9029-40. doi: 10.1128/jvi.77.16.9029-9040.2003. J Virol. 2003. PMID: 12885919 Free PMC article.
40 results