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2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles.
Lin H, Yamashita DS, Zeng J, Xie R, Verma S, Luengo JI, Rhodes N, Zhang S, Robell KA, Choudhry AE, Lai Z, Kumar R, Minthorn EA, Brown KK, Heerding DA. Lin H, et al. Among authors: verma s. Bioorg Med Chem Lett. 2010 Jan 15;20(2):679-83. doi: 10.1016/j.bmcl.2009.11.060. Epub 2009 Nov 20. Bioorg Med Chem Lett. 2010. PMID: 20005102
Tetrasubstituted pyridines as potent and selective AKT inhibitors: Reduced CYP450 and hERG inhibition of aminopyridines.
Lin H, Yamashita DS, Xie R, Zeng J, Wang W, Leber J, Safonov IG, Verma S, Li M, Lafrance L, Venslavsky J, Takata D, Luengo JI, Kahana JA, Zhang S, Robell KA, Levy D, Kumar R, Choudhry AE, Schaber M, Lai Z, Brown BS, Donovan BT, Minthorn EA, Brown KK, Heerding DA. Lin H, et al. Among authors: verma s. Bioorg Med Chem Lett. 2010 Jan 15;20(2):684-8. doi: 10.1016/j.bmcl.2009.11.061. Epub 2009 Dec 16. Bioorg Med Chem Lett. 2010. PMID: 20006500
Association between overweight and obesity with coronary artery bypass graft failure: an individual patient data analysis of clinical trials.
An KR, Sandner S, Redfors B, Alexander JH, Alzghari T, Caldonazo T, Cancelli G, Dell'Aquila M, Dimagli A, Gibson CM, Harik L, Heise R, Kulik A, Lamy A, Leith J, Peper J, Perezgrovas-Olaria R, Rossi CS, Ruel M, Soletti G Jr, Ten Berg JM, Willemsen LM, Wojdyla DM, Zhao Q, Zhu Y, Verma S, Gaudino MFL. An KR, et al. Among authors: verma s. Eur J Cardiothorac Surg. 2024 Jun 3:ezae221. doi: 10.1093/ejcts/ezae221. Online ahead of print. Eur J Cardiothorac Surg. 2024. PMID: 38830050
6,436 results