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Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase.
Bioorg Med Chem Lett. 2005 Apr 15;15(8):1997-2001. doi: 10.1016/j.bmcl.2005.02.067.
Bioorg Med Chem Lett. 2005.
PMID: 15808455
Pyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation.
Debenham JS, Madsen-Duggan CB, Wang J, Tong X, Lao J, Fong TM, Schaeffer MT, Xiao JC, Huang CC, Shen CP, Sloan Stribling D, Shearman LP, Strack AM, Euan Macintyre D, Hale JJ, Walsh TF.
Debenham JS, et al. Among authors: euan macintyre d.
Bioorg Med Chem Lett. 2009 May 1;19(9):2591-4. doi: 10.1016/j.bmcl.2009.03.005. Epub 2009 Mar 9.
Bioorg Med Chem Lett. 2009.
PMID: 19328684
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3-Amino-1,5-benzodiazepinones: potent, state-dependent sodium channel blockers with anti-epileptic activity.
Hoyt SB, London C, Wyvratt MJ, Fisher MH, Cashen DE, Felix JP, Garcia ML, Li X, Lyons KA, Euan MacIntyre D, Martin WJ, Priest BT, Smith MM, Warren VA, Williams BS, Kaczorowski GJ, Parsons WH.
Hoyt SB, et al. Among authors: euan macintyre d.
Bioorg Med Chem Lett. 2008 Mar 15;18(6):1963-6. doi: 10.1016/j.bmcl.2008.01.123. Epub 2008 Feb 7.
Bioorg Med Chem Lett. 2008.
PMID: 18289851
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Structure-activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat.
Ye Z, MacNeil T, Weinberg DH, Kalyani RN, Tang R, Strack AM, Murphy BA, Mosley RT, Euan MacIntyre D, Van der Ploeg LH, Patchett AA, Wyvratt MJ, Nargund RP.
Ye Z, et al. Among authors: euan macintyre d.
Peptides. 2005 Oct;26(10):2017-25. doi: 10.1016/j.peptides.2004.12.035.
Peptides. 2005.
PMID: 15993513
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Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
Abbadie C, McManus OB, Sun SY, Bugianesi RM, Dai G, Haedo RJ, Herrington JB, Kaczorowski GJ, Smith MM, Swensen AM, Warren VA, Williams B, Arneric SP, Eduljee C, Snutch TP, Tringham EW, Jochnowitz N, Liang A, Euan MacIntyre D, McGowan E, Mistry S, White VV, Hoyt SB, London C, Lyons KA, Bunting PB, Volksdorf S, Duffy JL.
Abbadie C, et al. Among authors: euan macintyre d.
J Pharmacol Exp Ther. 2010 Aug;334(2):545-55. doi: 10.1124/jpet.110.166363. Epub 2010 May 3.
J Pharmacol Exp Ther. 2010.
PMID: 20439438
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