Pachón G - Search Results

1

DNA damage induced by a quinoxaline 1,4-di-N-oxide derivative (hypoxic selective agent) in Caco-2 cells evaluated by the comet assay.

Azqueta A, Pachón G, Cascante M, Creppy EE, López de Cerain A. Azqueta A, et al. Among authors: pachon g. Mutagenesis. 2005 May;20(3):165-71. doi: 10.1093/mutage/gei023. Epub 2005 Apr 7. Mutagenesis. 2005. PMID: 15817574

2

Selective toxicity of a quinoxaline 1,4-di-N-oxide derivative in human tumour cell lines.

Amaia A, Pachón G, Cascante M, Creppy EE, Monge A, López de Cerain A. Amaia A, et al. Among authors: pachon g. Arzneimittelforschung. 2005;55(3):177-82. doi: 10.1055/s-0031-1296841. Arzneimittelforschung. 2005. PMID: 15819391

3

A quinoxaline 1,4-di-N-oxide derivative induces DNA oxidative damage not attenuated by vitamin C and E treatment.

Azqueta A, Arbillaga L, Pachón G, Cascante M, Creppy EE, López de Cerain A. Azqueta A, et al. Among authors: pachon g. Chem Biol Interact. 2007 Jun 30;168(2):95-105. doi: 10.1016/j.cbi.2007.02.013. Epub 2007 Mar 4. Chem Biol Interact. 2007. PMID: 17420013

4

Study of benzo[a]phenazine 7,12-dioxide as selective hypoxic cytotoxin-scaffold. Identification of aerobic-antitumoral activity through DNA fragmentation.

Lavaggi ML, Cabrera M, Aravena Mde L, Olea-Azar C, López de Ceráin A, Monge A, Pachón G, Cascante M, Bruno AM, Pietrasanta LI, González M, Cerecetto H. Lavaggi ML, et al. Among authors: pachon g. Bioorg Med Chem. 2010 Jun 15;18(12):4433-40. doi: 10.1016/j.bmc.2010.04.074. Epub 2010 Apr 26. Bioorg Med Chem. 2010. PMID: 20471844

5

Anticancer effect of a new benzophenanthridine isolated from Zanthoxylum madagascariense (Rutaceline).

Pachon G, Rasoanaivo H, Azqueta A, Rakotozafy JC, Raharisololalao A, De Cerain AL, De Lapuente J, Borràs M, Moukha S, Centelles JJ, Creppy EE, Cascante M. Pachon G, et al. In Vivo. 2007 Mar-Apr;21(2):417-22. In Vivo. 2007. PMID: 17436597 Free article.

6

Unveiling the Metabolic Changes on Muscle Cell Metabolism Underlying p-Phenylenediamine Toxicity.

Marín de Mas I, Marín S, Pachón G, Rodríguez-Prados JC, Vizán P, Centelles JJ, Tauler R, Azqueta A, Selivanov V, López de Ceraín A, Cascante M. Marín de Mas I, et al. Among authors: pachon g. Front Mol Biosci. 2017 Mar 6;4:8. doi: 10.3389/fmolb.2017.00008. eCollection 2017. Front Mol Biosci. 2017. PMID: 28321398 Free PMC article.

7

New betulinic acid derivatives induce potent and selective antiproliferative activity through cell cycle arrest at the S phase and caspase dependent apoptosis in human cancer cells.

Santos RC, Salvador JA, Cortés R, Pachón G, Marín S, Cascante M. Santos RC, et al. Among authors: pachon g. Biochimie. 2011 Jun;93(6):1065-75. doi: 10.1016/j.biochi.2011.02.014. Epub 2011 Mar 4. Biochimie. 2011. PMID: 21377507

8

Novel Phenazine 5,10-Dioxides Release OH in Simulated Hypoxia and Induce Reduction of Tumour Volume In Vivo.

Lavaggi ML, Cabrera M, Pintos C, Arredondo C, Pachón G, Rodríguez J, Raymondo S, Pacheco JP, Cascante M, Olea-Azar C, López de Ceráin A, Monge A, Cerecetto H, González M. Lavaggi ML, et al. Among authors: pachon g. ISRN Pharmacol. 2011;2011:314209. doi: 10.5402/2011/314209. Epub 2011 Jun 22. ISRN Pharmacol. 2011. PMID: 22084710 Free PMC article.

9

Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis.

Ejarque M, Ceperuelo-Mallafré V, Serena C, Pachón G, Núñez-Álvarez Y, Terrón-Puig M, Calvo E, Núñez-Roa C, Oliva-Olivera W, Tinahones FJ, Peinado MA, Vendrell J, Fernández-Veledo S. Ejarque M, et al. Among authors: pachon g. Cell Death Dis. 2017 May 18;8(5):e2802. doi: 10.1038/cddis.2017.209. Cell Death Dis. 2017. PMID: 28518147 Free PMC article.

10

Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.

Ceperuelo-Mallafré V, Ejarque M, Duran X, Pachón G, Vázquez-Carballo A, Roche K, Núñez-Roa C, Garrido-Sánchez L, Tinahones FJ, Vendrell J, Fernández-Veledo S. Ceperuelo-Mallafré V, et al. Among authors: pachon g. PLoS One. 2015 Jun 11;10(6):e0129644. doi: 10.1371/journal.pone.0129644. eCollection 2015. PLoS One. 2015. PMID: 26068931 Free PMC article.

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