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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, Boggon TJ, Wlodarska I, Clark JJ, Moore S, Adelsperger J, Koo S, Lee JC, Gabriel S, Mercher T, D'Andrea A, Fröhling S, Döhner K, Marynen P, Vandenberghe P, Mesa RA, Tefferi A, Griffin JD, Eck MJ, Sellers WR, Meyerson M, Golub TR, Lee SJ, Gilliland DG. Levine RL, et al. Among authors: vandenberghe p. Cancer Cell. 2005 Apr;7(4):387-97. doi: 10.1016/j.ccr.2005.03.023. Cancer Cell. 2005. PMID: 15837627 Free article.
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.
Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J, Kutok J, Clark J, Galinsky I, Griffin JD, Cross NC, Tefferi A, Malone J, Alam R, Schrier SL, Schmid J, Rose M, Vandenberghe P, Verhoef G, Boogaerts M, Wlodarska I, Kantarjian H, Marynen P, Coutre SE, Stone R, Gilliland DG. Cools J, et al. Among authors: vandenberghe p. N Engl J Med. 2003 Mar 27;348(13):1201-14. doi: 10.1056/NEJMoa025217. N Engl J Med. 2003. PMID: 12660384 Free article.
Genomic alterations of the JAK2 and PDL loci occur in a broad spectrum of lymphoid malignancies.
Van Roosbroeck K, Ferreiro JF, Tousseyn T, van der Krogt JA, Michaux L, Pienkowska-Grela B, Theate I, De Paepe P, Dierickx D, Doyen C, Put N, Cools J, Vandenberghe P, Wlodarska I. Van Roosbroeck K, et al. Among authors: vandenberghe p. Genes Chromosomes Cancer. 2016 May;55(5):428-41. doi: 10.1002/gcc.22345. Epub 2016 Feb 6. Genes Chromosomes Cancer. 2016. PMID: 26850007 Free article.
FER and FES tyrosine kinase fusions in follicular T-cell lymphoma.
Debackere K, van der Krogt JA, Tousseyn T, Ferreiro JAF, Van Roosbroeck K, Marcelis L, Graux C, Dierickx D, Ameye G, Vandenberghe P, Michaux L, Cools J, Wlodarska I. Debackere K, et al. Among authors: vandenberghe p. Blood. 2020 Feb 20;135(8):584-588. doi: 10.1182/blood.2019002401. Blood. 2020. PMID: 31746983 Free article. No abstract available.
Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.
Dewaele B, Wasag B, Cools J, Sciot R, Prenen H, Vandenberghe P, Wozniak A, Schöffski P, Marynen P, Debiec-Rychter M. Dewaele B, et al. Among authors: vandenberghe p. Clin Cancer Res. 2008 Sep 15;14(18):5749-58. doi: 10.1158/1078-0432.CCR-08-0533. Clin Cancer Res. 2008. PMID: 18794084
New flow cytometry in hematologic malignancies.
Cools J, Vandenberghe P. Cools J, et al. Among authors: vandenberghe p. Haematologica. 2009 Dec;94(12):1639-41. doi: 10.3324/haematol.2009.013482. Haematologica. 2009. PMID: 19996114 Free PMC article.
ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions.
Van Roosbroeck K, Cools J, Dierickx D, Thomas J, Vandenberghe P, Stul M, Delabie J, De Wolf-Peeters C, Marynen P, Wlodarska I. Van Roosbroeck K, et al. Among authors: vandenberghe p. Haematologica. 2010 Mar;95(3):509-13. doi: 10.3324/haematol.2009.014761. Haematologica. 2010. PMID: 20207848 Free PMC article.
313 results