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Discovery of a beta-MSH-derived MC-4R selective agonist.
J Med Chem. 2005 May 5;48(9):3095-8. doi: 10.1021/jm0501432.
J Med Chem. 2005.
PMID: 15857110
Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold.
Yan LZ, Flora D, Edwards P, Smiley DL, Emmerson PJ, Hsiung HM, Gadski R, Hertel J, Heiman ML, Husain S, O'Brien TP, Kahl SD, Zhang L, Dimarchi RD, Mayer JP.
Yan LZ, et al.
Bioorg Med Chem Lett. 2005 Oct 15;15(20):4611-4. doi: 10.1016/j.bmcl.2005.06.081.
Bioorg Med Chem Lett. 2005.
PMID: 16105738
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A novel and selective beta-melanocyte-stimulating hormone-derived peptide agonist for melanocortin 4 receptor potently decreased food intake and body weight gain in diet-induced obese rats.
Hsiung HM, Hertel J, Zhang XY, Smith DP, Smiley DL, Heiman ML, Yang DD, Husain S, Mayer JP, Zhang L, Mo H, Yan LZ.
Hsiung HM, et al.
Endocrinology. 2005 Dec;146(12):5257-66. doi: 10.1210/en.2005-0177. Epub 2005 Sep 15.
Endocrinology. 2005.
PMID: 16166226
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Structure-activity relationships of beta-MSH derived melanocortin-4 receptor peptide agonists.
Yan LZ, Hsiung HM, Heiman ML, Gadski RA, Emmerson PJ, Hertel J, Flora D, Edwards P, Smiley D, Zhang L, Husain S, Kahl SD, DiMarchi RD, Mayer JP.
Yan LZ, et al.
Curr Top Med Chem. 2007;7(11):1052-67. doi: 10.2174/156802607780906591.
Curr Top Med Chem. 2007.
PMID: 17584126
Review.
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Fat and water 1H MRI to investigate effects of leptin in obese mice.
James JR, Hertel JL, Babsky AM, Hekmatyar SK, Heiman ML, Jackson CV, Bansal N.
James JR, et al. Among authors: hertel jl.
Obesity (Silver Spring). 2009 Nov;17(11):2089-93. doi: 10.1038/oby.2009.133. Epub 2009 Apr 30.
Obesity (Silver Spring). 2009.
PMID: 19407808
Free article.
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