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The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).
Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR Jr, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'neill KA, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA. Garcia-Calvo M, et al. Among authors: iyer sp. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. doi: 10.1073/pnas.0500269102. Epub 2005 May 31. Proc Natl Acad Sci U S A. 2005. PMID: 15928087 Free PMC article.
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Davis HR Jr, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, Liu J, Yao X, Iyer SP, Lam MH, Lund EG, Detmers PA, Graziano MP, Altmann SW. Davis HR Jr, et al. Among authors: iyer sp. J Biol Chem. 2004 Aug 6;279(32):33586-92. doi: 10.1074/jbc.M405817200. Epub 2004 Jun 1. J Biol Chem. 2004. PMID: 15173162 Free article.
Optical genomic mapping is a helpful tool for detecting CCND1 rearrangements in CD5-negative small B-cell lymphoma: Two cases of leukemic non-nodal mantle cell lymphoma.
Quesada AE, Hu S, Li S, Toruner GA, Wei Q, Loghavi S, Ok CY, Jain P, Thakral B, Nwogbo OV, Kim D, Iyer SP, You MJ, Medeiros LJ, Tang G. Quesada AE, et al. Among authors: iyer sp. Hum Pathol. 2024 Feb;144:71-76. doi: 10.1016/j.humpath.2024.01.012. Epub 2024 Jan 30. Hum Pathol. 2024. PMID: 38301962
Efficacy and safety of brexucabtagene autoleucel CAR T-cell therapy with BTK inhibitors in the treatment of relapsed mantle cell lymphoma with central nervous system involvement.
Lionel AC, Gurumurthi A, Fetooh A, Eldaya R, Ahmed S, Iyer SP, Nastoupil LJ, Westin J, Nair R, Fayad L, Malpica L, Tummala S, Flowers C, Neelapu SS, Wang ML, Jain P. Lionel AC, et al. Among authors: iyer sp. Leuk Lymphoma. 2024 May;65(5):669-673. doi: 10.1080/10428194.2024.2304622. Epub 2024 Jan 22. Leuk Lymphoma. 2024. PMID: 38248629 No abstract available.
125 results