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Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).
Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, Oliver RL, Millington G, Aparicio SA, Colledge WH, Russ AP, Carlton MB, O'Rahilly S. Challis BG, et al. Among authors: thresher rr. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4695-700. doi: 10.1073/pnas.0306931101. Epub 2004 Mar 15. Proc Natl Acad Sci U S A. 2004. PMID: 15070780 Free PMC article.
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.
Medina-Gomez G, Virtue S, Lelliott C, Boiani R, Campbell M, Christodoulides C, Perrin C, Jimenez-Linan M, Blount M, Dixon J, Zahn D, Thresher RR, Aparicio S, Carlton M, Colledge WH, Kettunen MI, Seppänen-Laakso T, Sethi JK, O'Rahilly S, Brindle K, Cinti S, Oresic M, Burcelin R, Vidal-Puig A. Medina-Gomez G, et al. Among authors: thresher rr. Diabetes. 2005 Jun;54(6):1706-16. doi: 10.2337/diabetes.54.6.1706. Diabetes. 2005. PMID: 15919792 Free PMC article.
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54.
Messager S, Chatzidaki EE, Ma D, Hendrick AG, Zahn D, Dixon J, Thresher RR, Malinge I, Lomet D, Carlton MB, Colledge WH, Caraty A, Aparicio SA. Messager S, et al. Among authors: thresher rr. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1761-6. doi: 10.1073/pnas.0409330102. Epub 2005 Jan 21. Proc Natl Acad Sci U S A. 2005. PMID: 15665093 Free PMC article.
The GPR54 gene as a regulator of puberty.
Seminara SB, Messager S, Chatzidaki EE, Thresher RR, Acierno JS Jr, Shagoury JK, Bo-Abbas Y, Kuohung W, Schwinof KM, Hendrick AG, Zahn D, Dixon J, Kaiser UB, Slaugenhaupt SA, Gusella JF, O'Rahilly S, Carlton MB, Crowley WF Jr, Aparicio SA, Colledge WH. Seminara SB, et al. Among authors: thresher rr. N Engl J Med. 2003 Oct 23;349(17):1614-27. doi: 10.1056/NEJMoa035322. N Engl J Med. 2003. PMID: 14573733 Free article.
Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties.
Hakim P, Gurung IS, Pedersen TH, Thresher R, Brice N, Lawrence J, Grace AA, Huang CL. Hakim P, et al. Among authors: thresher r. Prog Biophys Mol Biol. 2008 Oct-Nov;98(2-3):251-66. doi: 10.1016/j.pbiomolbio.2009.01.005. Epub 2009 Jan 24. Prog Biophys Mol Biol. 2008. PMID: 19351516 Free PMC article.
62 results