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4-Fluorosulfonylpiperidines: selective 5-HT2A ligands for the treatment of insomnia.
Fish LR, Gilligan MT, Humphries AC, Ivarsson M, Ladduwahetty T, Merchant KJ, O'Connor D, Patel S, Philipps E, Vargas HM, Hutson PH, MacLeod AM. Fish LR, et al. Among authors: patel s. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3665-9. doi: 10.1016/j.bmcl.2005.05.104. Bioorg Med Chem Lett. 2005. PMID: 15993598
4-(Phenylsulfonyl)piperidines: novel, selective, and bioavailable 5-HT(2A) receptor antagonists.
Fletcher SR, Burkamp F, Blurton P, Cheng SK, Clarkson R, O'Connor D, Spinks D, Tudge M, van Niel MB, Patel S, Chapman K, Marwood R, Shepheard S, Bentley G, Cook GP, Bristow LJ, Castro JL, Hutson PH, MacLeod AM. Fletcher SR, et al. Among authors: patel s. J Med Chem. 2002 Jan 17;45(2):492-503. doi: 10.1021/jm011030v. J Med Chem. 2002. PMID: 11784153
A new class of selective, non-basic 5-HT2A receptor antagonists.
Ladduwahetty T, Boase AL, Mitchinson A, Quin C, Patel S, Chapman K, MacLeod AM. Ladduwahetty T, et al. Among authors: patel s. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3201-4. doi: 10.1016/j.bmcl.2006.03.050. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16632354
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