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Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.
Camps M, Rückle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Françon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C. Camps M, et al. Among authors: shaw j. Nat Med. 2005 Sep;11(9):936-43. doi: 10.1038/nm1284. Epub 2005 Aug 28. Nat Med. 2005. PMID: 16127437 Free article.
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.
Pomel V, Klicic J, Covini D, Church DD, Shaw JP, Roulin K, Burgat-Charvillon F, Valognes D, Camps M, Chabert C, Gillieron C, Françon B, Perrin D, Leroy D, Gretener D, Nichols A, Vitte PA, Carboni S, Rommel C, Schwarz MK, Rückle T. Pomel V, et al. Among authors: shaw jp. J Med Chem. 2006 Jun 29;49(13):3857-71. doi: 10.1021/jm0601598. J Med Chem. 2006. PMID: 16789742
Glycosaminoglycan analogs as a novel anti-inflammatory strategy.
Severin IC, Soares A, Hantson J, Teixeira M, Sachs D, Valognes D, Scheer A, Schwarz MK, Wells TN, Proudfoot AE, Shaw J. Severin IC, et al. Among authors: shaw j. Front Immunol. 2012 Oct 16;3:293. doi: 10.3389/fimmu.2012.00293. eCollection 2012. Front Immunol. 2012. PMID: 23087686 Free PMC article.
Chemokine blockers--therapeutics in the making?
Wells TN, Power CA, Shaw JP, Proudfoot AE. Wells TN, et al. Trends Pharmacol Sci. 2006 Jan;27(1):41-7. doi: 10.1016/j.tips.2005.11.001. Epub 2005 Nov 28. Trends Pharmacol Sci. 2006. PMID: 16310864 Review.
Ticks produce highly selective chemokine binding proteins with antiinflammatory activity.
Déruaz M, Frauenschuh A, Alessandri AL, Dias JM, Coelho FM, Russo RC, Ferreira BR, Graham GJ, Shaw JP, Wells TN, Teixeira MM, Power CA, Proudfoot AE. Déruaz M, et al. Among authors: shaw jp. J Exp Med. 2008 Sep 1;205(9):2019-31. doi: 10.1084/jem.20072689. Epub 2008 Aug 4. J Exp Med. 2008. PMID: 18678732 Free PMC article.
5,941 results