Demarest J - Search Results

1

Antiviral activity and safety of 873140, a novel CCR5 antagonist, during short-term monotherapy in HIV-infected adults.

Lalezari J, Thompson M, Kumar P, Piliero P, Davey R, Patterson K, Shachoy-Clark A, Adkison K, Demarest J, Lou Y, Berrey M, Piscitelli S. Lalezari J, et al. Among authors: demarest j. AIDS. 2005 Sep 23;19(14):1443-8. doi: 10.1097/01.aids.0000183633.06580.8a. AIDS. 2005. PMID: 16135896 Clinical Trial.

2

In vitro and clinical investigation of the relationship between CCR5 receptor occupancy and anti-HIV activity of Aplaviroc.

Demarest JF, Sparks SS, Schell K, Shibayama S, McDanal CB, Fang L, Adkison KK, Shachoy-Clark A, Piscitelli SC. Demarest JF, et al. J Clin Pharmacol. 2008 Oct;48(10):1179-88. doi: 10.1177/0091270008322178. Epub 2008 Aug 1. J Clin Pharmacol. 2008. PMID: 18676693 Clinical Trial.

3

Perspectives on the Barrier to Resistance for Dolutegravir + Lamivudine, a Two-Drug Antiretroviral Therapy for HIV-1 Infection.

Boffito M, Waters L, Cahn P, Paredes R, Koteff J, Van Wyk J, Vincent T, Demarest J, Adkison K, Quercia R. Boffito M, et al. Among authors: demarest j. AIDS Res Hum Retroviruses. 2020 Jan;36(1):13-18. doi: 10.1089/AID.2019.0171. Epub 2019 Oct 21. AIDS Res Hum Retroviruses. 2020. PMID: 31507204 Free PMC article. Review.

4

Chemokine (C-C motif) receptor 5-using envelopes predominate in dual/mixed-tropic HIV from the plasma of drug-naive individuals.

Irlbeck DM, Amrine-Madsen H, Kitrinos KM, Labranche CC, Demarest JF. Irlbeck DM, et al. AIDS. 2008 Jul 31;22(12):1425-31. doi: 10.1097/QAD.0b013e32830184ba. AIDS. 2008. PMID: 18614865

5

HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry.

Tilton JC, Amrine-Madsen H, Miamidian JL, Kitrinos KM, Pfaff J, Demarest JF, Ray N, Jeffrey JL, Labranche CC, Doms RW. Tilton JC, et al. Among authors: demarest jf. AIDS Res Hum Retroviruses. 2010 Jan;26(1):13-24. doi: 10.1089/aid.2009.0132. AIDS Res Hum Retroviruses. 2010. PMID: 20055594 Free PMC article.

6

HIV-1 infection in the lymphoid organs.

Graziosi C, Pantaleo G, Demarest JF, Cohen OJ, Vaccarezza M, Butini L, Montroni M, Fauci AS. Graziosi C, et al. Among authors: demarest jf. AIDS. 1993 Nov;7 Suppl 2:S53-8. doi: 10.1097/00002030-199311002-00012. AIDS. 1993. PMID: 8161447 Review.

7

Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene.

Karlsson AC, Deeks SG, Barbour JD, Heiken BD, Younger SR, Hoh R, Lane M, Sällberg M, Ortiz GM, Demarest JF, Liegler T, Grant RM, Martin JN, Nixon DF. Karlsson AC, et al. J Virol. 2003 Jun;77(12):6743-52. doi: 10.1128/jvi.77.12.6743-6752.2003. J Virol. 2003. PMID: 12767994 Free PMC article.

8

Development of maraviroc, a CCR5 antagonist for treatment of HIV, using a novel tropism assay.

van der Ryst E, Heera J, Demarest J, Knirsch C. van der Ryst E, et al. Among authors: demarest j. Ann N Y Acad Sci. 2015 Jun;1346(1):7-17. doi: 10.1111/nyas.12777. Epub 2015 May 11. Ann N Y Acad Sci. 2015. PMID: 25962411

9

HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells.

Pfaff JM, Wilen CB, Harrison JE, Demarest JF, Lee B, Doms RW, Tilton JC. Pfaff JM, et al. J Virol. 2010 Jul;84(13):6505-14. doi: 10.1128/JVI.00374-10. Epub 2010 Apr 21. J Virol. 2010. PMID: 20410277 Free PMC article.

10

Virologic failure in first-line human immunodeficiency virus therapy with a CCR5 entry inhibitor, aplaviroc, plus a fixed-dose combination of lamivudine-zidovudine: nucleoside reverse transcriptase inhibitor resistance regardless of envelope tropism.

Demarest JF, Amrine-Madsen H, Irlbeck DM, Kitrinos KM; CCR102881 Clinical Study Team. Demarest JF, et al. Antimicrob Agents Chemother. 2009 Mar;53(3):1116-23. doi: 10.1128/AAC.01055-08. Epub 2008 Dec 15. Antimicrob Agents Chemother. 2009. PMID: 19075055 Free PMC article. Clinical Trial.

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