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Increased transcription and increased messenger ribonucleic acid (mRNA) stability contribute to increased GATA6 mRNA abundance in polycystic ovary syndrome theca cells.
Ho CK, Wood JR, Stewart DR, Ewens K, Ankener W, Wickenheisser J, Nelson-Degrave V, Zhang Z, Legro RS, Dunaif A, McAllister JM, Spielman R, Strauss JF 3rd. Ho CK, et al. Among authors: nelson degrave v. J Clin Endocrinol Metab. 2005 Dec;90(12):6596-602. doi: 10.1210/jc.2005-0890. Epub 2005 Sep 13. J Clin Endocrinol Metab. 2005. PMID: 16159937
Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome.
Nelson-Degrave VL, Wickenheisser JK, Hendricks KL, Asano T, Fujishiro M, Legro RS, Kimball SR, Strauss JF 3rd, McAllister JM. Nelson-Degrave VL, et al. Mol Endocrinol. 2005 Feb;19(2):379-90. doi: 10.1210/me.2004-0178. Epub 2004 Oct 28. Mol Endocrinol. 2005. PMID: 15514033
Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome.
Wickenheisser JK, Nelson-DeGrave VL, Hendricks KL, Legro RS, Strauss JF 3rd, McAllister JM. Wickenheisser JK, et al. Among authors: nelson degrave vl. J Clin Endocrinol Metab. 2005 Aug;90(8):4858-65. doi: 10.1210/jc.2005-0330. Epub 2005 May 24. J Clin Endocrinol Metab. 2005. PMID: 15914525
Human ovarian theca cells in culture.
Wickenheisser JK, Nelson-DeGrave VL, McAllister JM. Wickenheisser JK, et al. Among authors: nelson degrave vl. Trends Endocrinol Metab. 2006 Mar;17(2):65-71. doi: 10.1016/j.tem.2006.01.003. Epub 2006 Feb 7. Trends Endocrinol Metab. 2006. PMID: 16460956 Review.