Jacks T - Search Results

1

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.

Wijnhoven SW, Zwart E, Speksnijder EN, Beems RB, Olive KP, Tuveson DA, Jonkers J, Schaap MM, van den Berg J, Jacks T, van Steeg H, de Vries A. Wijnhoven SW, et al. Among authors: jacks t. Cancer Res. 2005 Sep 15;65(18):8166-73. doi: 10.1158/0008-5472.CAN-05-1650. Cancer Res. 2005. PMID: 16166291

2

Lessons from the p53 mutant mouse.

Jacks T. Jacks T. J Cancer Res Clin Oncol. 1996;122(6):319-27. doi: 10.1007/BF01220798. J Cancer Res Clin Oncol. 1996. PMID: 8642041 Review.

3

Modeling human lung cancer in mice: similarities and shortcomings.

Tuveson DA, Jacks T. Tuveson DA, et al. Among authors: jacks t. Oncogene. 1999 Sep 20;18(38):5318-24. doi: 10.1038/sj.onc.1203107. Oncogene. 1999. PMID: 10498884 Review.

4

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.

Johnson L, Mercer K, Greenbaum D, Bronson RT, Crowley D, Tuveson DA, Jacks T. Johnson L, et al. Among authors: jacks t. Nature. 2001 Apr 26;410(6832):1111-6. doi: 10.1038/35074129. Nature. 2001. PMID: 11323676

5

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.

Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA. Jackson EL, et al. Among authors: jacks t. Genes Dev. 2001 Dec 15;15(24):3243-8. doi: 10.1101/gad.943001. Genes Dev. 2001. PMID: 11751630 Free PMC article.

6

Technologically advanced cancer modeling in mice.

Tuveson DA, Jacks T. Tuveson DA, et al. Among authors: jacks t. Curr Opin Genet Dev. 2002 Feb;12(1):105-10. doi: 10.1016/s0959-437x(01)00272-6. Curr Opin Genet Dev. 2002. PMID: 11790563 Review.

7

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function.

de Vries A, Flores ER, Miranda B, Hsieh HM, van Oostrom CT, Sage J, Jacks T. de Vries A, et al. Among authors: jacks t. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2948-53. doi: 10.1073/pnas.052713099. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867759 Free PMC article.

8

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.

Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, Jacks T, Wright CV, Hruban RH, Lowy AM, Tuveson DA. Hingorani SR, et al. Among authors: jacks t. Cancer Cell. 2003 Dec;4(6):437-50. doi: 10.1016/s1535-6108(03)00309-x. Cancer Cell. 2003. PMID: 14706336 Free article.

9

Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer.

Attardi LD, de Vries A, Jacks T. Attardi LD, et al. Among authors: jacks t. Oncogene. 2004 Jan 29;23(4):973-80. doi: 10.1038/sj.onc.1207026. Oncogene. 2004. PMID: 14749764

10

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Kelly L, Shigematsu H, Johnson L, Akashi K, Tuveson DA, Jacks T, Gilliland DG. Chan IT, et al. Among authors: jacks t. J Clin Invest. 2004 Feb;113(4):528-38. doi: 10.1172/JCI20476. J Clin Invest. 2004. PMID: 14966562 Free PMC article.

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