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Down-regulation of hepatic HMG-CoA reductase in mice by dietary cholesterol: importance of the delta 5 double bond and evidence that oxidation at C-3, C-5, C-6, or C-7 is not involved.
Lund E, Björkhem I. Lund E, et al. Among authors: bjorkhem i. Biochemistry. 1994 Jan 11;33(1):291-7. doi: 10.1021/bi00167a038. Biochemistry. 1994. PMID: 8286350
It has been suggested that the down-regulation of hepatic HMG-CoA reductase by dietary cholesterol requires modification of the cholesterol molecule before it can exert its suppressive action. In a recent study [Lund, E., Breuer, O., & Bjorkhem, I. (1992) J. Bio …
It has been suggested that the down-regulation of hepatic HMG-CoA reductase by dietary cholesterol requires modification of the cholesterol …
561 results