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Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.
Shen J, Samul R, Silva RL, Akiyama H, Liu H, Saishin Y, Hackett SF, Zinnen S, Kossen K, Fosnaugh K, Vargeese C, Gomez A, Bouhana K, Aitchison R, Pavco P, Campochiaro PA. Shen J, et al. Among authors: pavco p. Gene Ther. 2006 Feb;13(3):225-34. doi: 10.1038/sj.gt.3302641. Gene Ther. 2006. PMID: 16195704
Pharmacokinetics of an antiangiogenic ribozyme (ANGIOZYME) in the mouse.
Sandberg JA, Bouhana KS, Gallegos AM, Agrawal AB, Grimm SL, Wincott FE, Reynolds MA, Pavco PA, Parry TJ. Sandberg JA, et al. Among authors: pavco pa. Antisense Nucleic Acid Drug Dev. 1999 Jun;9(3):271-7. doi: 10.1089/oli.1.1999.9.271. Antisense Nucleic Acid Drug Dev. 1999. PMID: 10435752
Ribozymes as tools for therapeutic target validation in arthritis.
Jarvis TC, Bouhana KS, Lesch ME, Brown SA, Parry TJ, Schrier DJ, Hunt SW 3rd, Pavco PA, Flory CM. Jarvis TC, et al. Among authors: pavco pa. J Immunol. 2000 Jul 1;165(1):493-8. doi: 10.4049/jimmunol.165.1.493. J Immunol. 2000. PMID: 10861088
Characterization of nuclease-resistant ribozymes directed against hepatitis B virus RNA.
Morrissey DV, Lee PA, Johnson DA, Overly SL, McSwiggen JA, Beigelman L, Mokler VR, Maloney L, Vargeese C, Bowman K, O'Brien JT, Shaffer CS, Conrad A, Schmid P, Morrey JD, Macejak DG, Pavco PA, Blatt LM. Morrissey DV, et al. Among authors: pavco pa. J Viral Hepat. 2002 Nov;9(6):411-8. doi: 10.1046/j.1365-2893.2002.00383.x. J Viral Hepat. 2002. PMID: 12431202
Novel hydrophobically modified asymmetric RNAi compounds (sd-rxRNA) demonstrate robust efficacy in the eye.
Byrne M, Tzekov R, Wang Y, Rodgers A, Cardia J, Ford G, Holton K, Pandarinathan L, Lapierre J, Stanney W, Bulock K, Shaw S, Libertine L, Fettes K, Khvorova A, Kaushal S, Pavco P. Byrne M, et al. Among authors: pavco p. J Ocul Pharmacol Ther. 2013 Dec;29(10):855-64. doi: 10.1089/jop.2013.0148. Epub 2013 Nov 1. J Ocul Pharmacol Ther. 2013. PMID: 24180627
Bioactivity of anti-angiogenic ribozymes targeting Flt-1 and KDR mRNA.
Parry TJ, Cushman C, Gallegos AM, Agrawal AB, Richardson M, Andrews LE, Maloney L, Mokler VR, Wincott FE, Pavco PA. Parry TJ, et al. Among authors: pavco pa. Nucleic Acids Res. 1999 Jul 1;27(13):2569-77. doi: 10.1093/nar/27.13.2569. Nucleic Acids Res. 1999. PMID: 10373571 Free PMC article.
24 results